The Enzyme Database

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EC 1.1.1.280     
Accepted name: (S)-3-hydroxyacid-ester dehydrogenase
Reaction: ethyl (S)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + NADPH + H+
Other name(s): 3-oxo ester (S)-reductase
Systematic name: ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase
Comments: Also acts on 4-oxo- and 5-oxo-fatty acids and their esters. cf. EC 1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 114705-03-2
References:
1.  Heidlas, J., Engel, K.-H. and Tressl, R. Purification and characterization of two oxidoreductases involved in the enantioselective reduction of 3-oxo, 4-oxo and 5-oxo esters in baker's yeast. Eur. J. Biochem. 172 (1988) 633–639. [PMID: 3280313]
[EC 1.1.1.280 created 1990 as EC 1.2.1.56, transferred 2003 to EC 1.1.1.280]
 
 


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