ExplorEnz: EC 1.14.20.5

Your query returned 1 entry. Printable version

1.14.20.5

Accepted name:

flavone synthase I

Reaction:

a flavanone + 2-oxoglutarate + O₂ = a flavone + succinate + CO₂ + H₂O

For diagram of flavonoid biosynthesis, click here and for diagram of the biosynthesis of naringenin derivatives, click here

Other name(s):

FNSI (gene name)

Systematic name:

flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating)

Comments:

The enzyme, which has been found in rice and in members of the Apiaceae (a plant family), is a member of the 2-oxoglutarate-dependent dioxygenases, and requires ascorbate and Fe²⁺ for full activity.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 138263-98-6

References:

1.	Martens, S., Forkmann, G., Matern, U. and Lukačin, R. Cloning of parsley flavone synthase I. Phytochemistry 58 (2001) 43–46. [DOI] [PMID: 11524111]
2.	Lukačin, R., Matern, U., Junghanns, K.T., Heskamp, M.L., Britsch, L., Forkmann, G. and Martens, S. Purification and antigenicity of flavone synthase I from irradiated parsley cells. Arch. Biochem. Biophys. 393 (2001) 177–183. [DOI] [PMID: 11516175]
3.	Martens, S., Forkmann, G., Britsch, L., Wellmann, F., Matern, U. and Lukačin, R. Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley. FEBS Lett. 544 (2003) 93–98. [DOI] [PMID: 12782296]

[EC 1.14.20.5 created 2004 as EC 1.14.11.22, transferred 2018 to EC 1.14.20.5]