EC |
2.3.1.268 |
Accepted name: |
ethanol O-acetyltransferase |
Reaction: |
ethanol + acetyl-CoA = ethyl acetate + CoA |
Other name(s): |
eat1 (gene name); ethanol acetyltransferase |
Systematic name: |
acetyl-CoA:ethanol O-acetyltransferase |
Comments: |
The enzyme, characterized from the yeast Wickerhamomyces anomalus, is responsible for most ethyl acetate synthesis in known ethyl acetate-producing yeasts. It is only distantly related to enzymes classified as EC 2.3.1.84, alcohol O-acetyltransferase. The enzyme also possesses thioesterase and esterase activities, which are inhibited by high ethanol concentrations. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Kruis, A.J., Levisson, M., Mars, A.E., van der Ploeg, M., Garces Daza, F., Ellena, V., Kengen, S.WM., van der Oost, J. and Weusthuis, R.A. Ethyl acetate production by the elusive alcohol acetyltransferase from yeast. Metab. Eng. 41 (2017) 92–101. [DOI] [PMID: 28356220] |
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[EC 2.3.1.268 created 2018] |
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