EC |
2.5.1.144 |
Accepted name: |
S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) |
Reaction: |
O-acetyl-L-serine + thiosulfate = S-sulfo-L-cysteine + acetate |
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For diagram of O3-Acetyl-L-serine metabolism, click here |
Glossary: |
O-acetyl-L-serine = (2S)-3-acetyloxy-2-aminopropanoic acid |
Other name(s): |
cysteine synthase B; cysM (gene name); CS26 (gene name) |
Systematic name: |
O-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase |
Comments: |
In plants, the activity is catalysed by a chloroplastic enzyme that plays an important role in chloroplast function and is essential for light-dependent redox regulation within the chloroplast. The bacterial enzyme also catalyses the activity of EC 2.5.1.47, cysteine synthase. cf. EC 2.8.5.1, S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
References: |
1. |
Hensel, G. and Truper, H.G. O-Acetylserine sulfhydrylase and S-sulfocysteine synthase activities of Rhodospirillum tenue. Arch. Microbiol. 134 (1983) 227–232. [PMID: 6615127] |
2. |
Nakamura, T., Iwahashi, H. and Eguchi, Y. Enzymatic proof for the identity of the S-sulfocysteine synthase and cysteine synthase B of Salmonella typhimurium. J. Bacteriol. 158 (1984) 1122–1127. [PMID: 6373737] |
3. |
Bermudez, M.A., Paez-Ochoa, M.A., Gotor, C. and Romero, L.C. Arabidopsis S-sulfocysteine synthase activity is essential for chloroplast function and long-day light-dependent redox control. Plant Cell 22 (2010) 403–416. [DOI] [PMID: 20179139] |
4. |
Bermudez, M.A., Galmes, J., Moreno, I., Mullineaux, P.M., Gotor, C. and Romero, L.C. Photosynthetic adaptation to length of day is dependent on S-sulfocysteine synthase activity in the thylakoid lumen. Plant Physiol. 160 (2012) 274–288. [DOI] [PMID: 22829322] |
5. |
Gotor, C. and Romero, L.C. S-Sulfocysteine synthase function in sensing chloroplast redox status. Plant Signal. Behav. 8:e23313 (2013). [DOI] [PMID: 23333972] |
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[EC 2.5.1.144 created 2018] |
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