ExplorEnz: EC 2.7.1.217

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2.7.1.217

Accepted name:

3-dehydrotetronate 4-kinase

Reaction:

(1) ATP + 3-dehydro-L-erythronate = ADP + 3-dehydro-4-phospho-L-erythronate
(2) ATP + 3-dehydro-D-erythronate = ADP + 3-dehydro-4-phospho-D-erythronate

For diagram of erythronate and threonate catabolism, click here

Glossary:

L-erythronate = (2S,3S)-2,3,4-trihydroxybutanoate
D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate

Other name(s):

otnK (gene name)

Systematic name:

ATP:3-dehydrotetronate 4-phosphotransferase

Comments:

The enzyme, characterized from bacteria, is involved in D-erythronate and L-threonate catabolism.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, PDB

References:

Zhang, X., Carter, M.S., Vetting, M.W., San Francisco, B., Zhao, S., Al-Obaidi, N.F., Solbiati, J.O., Thiaville, J.J., de Crecy-Lagard, V., Jacobson, M.P., Almo, S.C. and Gerlt, J.A. Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars. Proc. Natl. Acad. Sci. USA 113 (2016) E4161–E4169. [DOI] [PMID: 27402745]

[EC 2.7.1.217 created 2017]