The Enzyme Database

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EC 2.8.5.1     
Accepted name: S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent)
Reaction: O-phospho-L-serine + thiosulfate = S-sulfo-L-cysteine + phosphate
Other name(s): cysK2 (gene name)
Systematic name: thiosulfate:3-phospho-L-serine thiosulfotransferase
Comments: The enzyme, which has been characterized from the bacterium Mycobacterium tuberculosis, has no activity with O-acetyl-L-serine. Requires pyridoxal 5′-phosphate. cf. EC 2.5.1.144, S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Steiner, E.M., Both, D., Lossl, P., Vilaplana, F., Schnell, R. and Schneider, G. CysK2 from Mycobacterium tuberculosis is an O-phospho-L-serine-dependent S-sulfocysteine synthase. J. Bacteriol. 196 (2014) 3410–3420. [DOI] [PMID: 25022854]
[EC 2.8.5.1 created 2018]
 
 


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