ExplorEnz: EC 3.1.3.49

3.1.3.49

Accepted name:

[pyruvate kinase]-phosphatase

Reaction:

[pyruvate kinase] phosphate + H₂O = [pyruvate kinase] + phosphate

Other name(s):

pyruvate kinase phosphatase

Systematic name:

[ATP:pyruvate 2-O-phosphotransferase]-phosphate phosphohydrolase

Comments:

Simultaneously dephosphorylates and activates EC 2.7.1.40 pyruvate kinase, that has been inactivated by protein kinase.

References:

1.	Jett, M.-F., Hue, L. and Hers, H.-G. Pyruvate kinase phosphatase. FEBS Lett. 132 (1981) 183–186. [PMID: 6271587]

[EC 3.1.3.49 created 1984]