| EC |
3.4.24.43 |
| Accepted name: |
atroxase |
| Reaction: |
Cleavage of His5┼Leu, Ser9┼His, His10┼Leu, Ala14┼Leu and Tyr16┼Leu of insulin B chain |
| Comments: |
A nonhemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that cleaves fibrinogen. In peptidase family M12 (astacin family) |
| References: |
| 1. |
Willis, T.W. and Tu, A.T. Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom. Biochemistry 27 (1988) 4769–4777. [PMID: 3167016] |
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| [EC 3.4.24.43 created 1992] |
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