EC |
3.5.1.43 |
Accepted name: |
peptidyl-glutaminase |
Reaction: |
α-N-peptidyl-L-glutamine + H2O = α-N-peptidyl-L-glutamate + NH3 |
Other name(s): |
peptidoglutaminase I; peptideglutaminase; peptidoglutaminase |
Systematic name: |
peptidyl-L-glutamine amidohydrolase |
Comments: |
Specific for the hydrolysis of the γ-amide of glutamine substituted at the α-amino group, e.g., glycyl-L-glutamine, N-acetyl-L-glutamine and L-leucylglycyl-L-glutamine. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37228-70-9 |
References: |
1. |
Kikuchi, M., Hayashida, H., Nakano, E. and Sakaguchi, K. Peptidoglutaminase. Enzymes for selective deamidation of γ-amide of peptide-bound glutamine. Biochemistry 10 (1971) 1222–1229. [PMID: 4928623] |
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[EC 3.5.1.43 created 1976] |
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