The enzyme from Methanopyrus kandleri specifically catalyses the deamination of cytosine at position 8 of tRNA in 30 different tRNAs. This cytosine-to-uracil editing guarantees the proper folding and functionality of the tRNAs.
References:
1.
Randau, L., Stanley, B.J., Kohlway, A., Mechta, S., Xiong, Y. and Söll, D. A cytidine deaminase edits C to U in transfer RNAs in Archaea. Science324 (2009) 657–659. [PMID: 19407206]