| EC |
3.6.1.64 |
| Accepted name: |
inosine diphosphate phosphatase |
| Reaction: |
(1) IDP + H2O = IMP + phosphate
(2) dIDP + H2O = dIMP + phosphate |
| Other name(s): |
(deoxy)inosine diphosphatase; NUDT16 |
| Systematic name: |
inosine diphosphate phosphatase |
| Comments: |
The human enzyme also hydrolyses GDP and dGDP, and to a lesser extent ITP, dITP and XTP. |
| References: |
| 1. |
Iyama, T., Abolhassani, N., Tsuchimoto, D., Nonaka, M. and Nakabeppu, Y. NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest. Nucleic Acids Res. 38 (2010) 4834–4843. [PMID: 20385596] |
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| [EC 3.6.1.64 created 2013] |
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