| EC |
4.1.1.110 |
| Accepted name: |
bisphosphomevalonate decarboxylase |
| Reaction: |
(R)-3,5-bisphosphomevalonate = isopentenyl phosphate + CO2 + phosphate |
| Other name(s): |
mevalonate 3,5-bisphosphate decarboxylase |
| Systematic name: |
(R)-3,5-bisphosphomevalonate carboxy-lyase (isopentenyl-phosphate-forming) |
| Comments: |
The enzyme participates in an alternative mevalonate pathway that takes place in extreme acidophiles of the Thermoplasmatales order. cf. EC 4.1.1.99, phosphomevalonate decarboxylase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Vinokur, J.M., Cummins, M.C., Korman, T.P. and Bowie, J.U. An adaptation to life in acid through a novel mevalonate pathway. Sci. Rep. 6 (2016) 39737. [DOI] [PMID: 28004831] |
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| [EC 4.1.1.110 created 2018] |
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