| EC |
4.1.1.74 |
| Accepted name: |
indolepyruvate decarboxylase |
| Reaction: |
3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO2 |
| Glossary: |
thiamine diphosphate = 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-diphosphoethyl)-4-methyl-1,3-thiazolium |
| Other name(s): |
indol-3-yl-pyruvate carboxy-lyase; 3-(indol-3-yl)pyruvate carboxy-lyase |
| Systematic name: |
3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming] |
| Comments: |
Thiamine diphosphate- and Mg2+-dependent. More specific than EC 4.1.1.1 pyruvate decarboxylase |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9074-92-4 |
| References: |
| 1. |
Koga, J. Structure and function of indolepyruvate decarboxylase, a key enzyme in indole-3-pyruvic acid biosynthesis. Biochim. Biophys. Acta 1249 (1995) 1–13. [DOI] [PMID: 7766676] |
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| [EC 4.1.1.74 created 1999] |
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