| EC |
4.1.1.91 |
| Accepted name: |
salicylate decarboxylase |
| Reaction: |
salicylate = phenol + CO2 |
| Other name(s): |
salicylic acid decarboxylase; Scd |
| Systematic name: |
salicylate carboxy-lyase |
| Comments: |
In the reverse direction the enzyme catalyses the regioselective carboxylation of phenol into stoichiometric amounts of salicylate. The enzyme also catalyses the reversible decarboxylation of 2,4-dihydroxybenzoate, 2,6-dihydroxybenzoate, 2,3-dihydroxybenzoate and 4-aminosalicylate [1]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Kirimura, K., Gunji, H., Wakayama, R., Hattori, T. and Ishii, Y. Enzymatic Kolbe-Schmitt reaction to form salicylic acid from phenol: enzymatic characterization and gene identification of a novel enzyme, Trichosporon moniliiforme salicylic acid decarboxylase. Biochem. Biophys. Res. Commun. 394 (2010) 279–284. [DOI] [PMID: 20188702] |
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| [EC 4.1.1.91 created 2011] |
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