| EC |
4.2.3.56 |
| Accepted name: |
γ-humulene synthase |
| Reaction: |
(2E,6E)-farnesyl diphosphate = γ-humulene + diphosphate |
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For diagram of humulene-based sequiterpenoid biosynthesis, click here |
| Other name(s): |
humulene cyclase |
| Systematic name: |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (γ-humulene-forming) |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 110639-19-5 |
| References: |
| 1. |
Steele, C.L., Crock, J., Bohlmann, J. and Croteau, R. Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of δ-selinene synthase and γ-humulene synthase. J. Biol. Chem. 273 (1998) 2078–2089. [DOI] [PMID: 9442047] |
| 2. |
Little, D.B. and Croteau, R.B. Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases δ-selinene synthase and γ-humulene synthase. Arch. Biochem. Biophys. 402 (2002) 120–135. [DOI] [PMID: 12051690] |
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| [EC 4.2.3.56 created 2011] |
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