EC |
5.3.4.1 |
Accepted name: |
protein disulfide-isomerase |
Reaction: |
Catalyses the rearrangement of -S-S- bonds in proteins |
Other name(s): |
S-S rearrangase |
Systematic name: |
protein disulfide-isomerase |
Comments: |
Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37318-49-3 |
References: |
1. |
De Lorenzo, F., Goldberger, R.F., Steers, E., Givol, D. and Anfinsen, C.B. Purification and properties of an enzyme from beef liver which catalyzes sulfhydryl-disulfide interchange in proteins. J. Biol. Chem. 241 (1966) 1562–1567. [PMID: 5946614] |
2. |
Fuchs, S., De Lorenzo, F. and Anfinsen, C.B. Studies on the mechanism of the enzymic catalysis of disulfide interchange in proteins. J. Biol. Chem. 242 (1967) 398–402. [PMID: 6022836] |
|
[EC 5.3.4.1 created 1972] |
|
|
|
|