EC	6.6.1.1
Accepted name:	magnesium chelatase
Reaction:	ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+
Other name(s):	protoporphyrin IX magnesium-chelatase; protoporphyrin IX Mg-chelatase; magnesium-protoporphyrin IX chelatase; magnesium-protoporphyrin chelatase; magnesium-chelatase; Mg-chelatase; Mg-protoporphyrin IX magnesio-lyase
Systematic name:	Mg-protoporphyrin IX magnesium-lyase
Comments:	This is the first committed step of chlorophyll biosynthesis and is a branchpoint of two major routes in the tetrapyrrole pathway.
References:	1.  Walker, C.J. and Weinstein, J.D. In vitro assay of the chlorophyll biosynthetic enzyme Mg-chelatase: resolution of the activity into soluble and membrane-bound fractions. Proc. Natl. Acad. Sci. USA 88 (1991) 5789–5793. [PMID: 11607197] 2.  Walker, C.J. and Willows, R.D. Mechanism and regulation of Mg-chelatase. Biochem. J. 327 (1997) 321–333. [PMID: 9359397] 3.  Fodje, M.N., Hansson, A., Hansson, M., Olsen, J.G., Gough, S., Willows, R.D. and Al-Karadaghi, S. Interplay between an AAA module and an integrin I domain may regulate the function of magnesium chelatase. J. Mol. Biol. 311 (2001) 111–122. [PMID: 11469861]
[EC 6.6.1.1 created 2003]