| EC |
7.2.2.14 |
| Accepted name: |
P-type Mg2+ transporter |
| Reaction: |
ATP + H2O + Mg2+[side 1] = ADP + phosphate + Mg2+[side 2] |
| Other name(s): |
Mg2+-transporting P-type ATPase; Mg2+-transporting ATPase; Mg2+-importing ATPase; magnesium-translocating P-type ATPase; mgtA (gene name); mgtB (gene name) |
| Systematic name: |
ATP phosphohydrolase (P-type, Mg2+-importing) |
| Comments: |
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. A bacterial enzyme that imports Mg2+ with, rather than against, the Mg2+ electrochemical gradient. The enzyme is also involved in Ni2+ import. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Snavely, M.D., Miller, C.G. and Maguire, M.E. The mgtB Mg2+ transport locus of Salmonella typhimurium encodes a P-type ATPase. J. Biol. Chem. 266 (1991) 815–823. [PMID: 1824701] |
| 2. |
Maguire, M.E. MgtA and MgtB: prokaryotic P-type ATPases that mediate Mg2+ influx. J. Bioenerg. Biomembr. 24 (1992) 319–328. [PMID: 1328179] |
| 3. |
Tao, T., Snavely, M.D., Farr, S.G. and Maguire, M.E. Magnesium transport in Salmonella typhimurium: mtgA encodes a P-type ATPase and is regulated by Mg2+ in a manner similar to that of the mgtB P-type ATPase. J. Bacteriol. 177 (1995) 2654–2662. [DOI] [PMID: 7751273] |
|
| [EC 7.2.2.14 created 2000 as EC 3.6.3.2, modified 2001, transferred 2018 to EC 7.2.2.14] |
| |
|
| |
|
Printable version