The Enzyme Database

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EC 7.2.2.15     
Accepted name: P-type Ag+ transporter
Reaction: ATP + H2O + Ag+[side 1] = ADP + phosphate + Ag+[side 2]
Other name(s): Ag+-exporting ATPase
Systematic name: ATP phosphohydrolase (P-type, Ag+-exporting)
Comments: A P-type ATPase that exports Ag+ ions from some bacteria, archaea as well as from some animal tissues. The proteins also transport Cu+ ions (cf. EC 7.2.2.8, P-type Cu+ transporter).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Gupta, A., Matsui, K., Lo, J.F. and Silver, S. Molecular basis for resistance to silver cations in Salmonella. Nature Med. 5 (1999) 183–188. [DOI] [PMID: 9930866]
2.  Bury, N.R., Grosell, M., Grover, A.K. and Wood, C.M. ATP-dependent silver transport across the basolateral membrane of rainbow trout gills. Toxicol. Appl. Pharmacol. 159 (1999) 1–8. [DOI] [PMID: 10448119]
[EC 7.2.2.15 created 2000 as EC 3.6.3.53, transferred 2018 to EC 7.2.2.15]
 
 


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