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Your query returned 2 entries. 
Printable version
| EC | 1.14.13.121 | ||
| Transferred entry: | premnaspirodiene oxygenase. Now EC 1.14.14.151, premnaspirodiene oxygenase | ||
| EC | 1.14.14.151 | ||
| Accepted name: | premnaspirodiene oxygenase | ||
| Reaction: | (–)-vetispiradiene + 2 [reduced NADPH—hemoprotein reductase] + 2 O2 = solavetivone + 2 [oxidized NADPH—hemoprotein reductase] + 3 H2O (overall reaction) (1a) (–)-vetispiradiene + [reduced NADPH—hemoprotein reductase] + O2 = solavetivol + [oxidized NADPH—hemoprotein reductase] + H2O (1b) solavetivol + [reduced NADPH—hemoprotein reductase] + O2 = solavetivone + [oxidized NADPH—hemoprotein reductase] + 2 H2O |
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| For diagram of solavetivone biosynthesis, click here | |||
| Glossary: | (–)-premnaspirodiene = (–)-vetispiradiene | ||
| Other name(s): | HPO; Hyoscymus muticus premnaspirodiene oxygenase; CYP71D55 | ||
| Systematic name: | (–)-vetispiradiene,[reduced NADPH—hemoprotein reductase]:oxygen 2α-oxidoreductase | ||
| Comments: | A cytochrome P-450 (heme-thiolate) protein. The enzyme from the plant Hyoscymus muticus also hydroxylates valencene at C-2 to give the α-hydroxy compound, nootkatol, and this is converted into nootkatone. 5-Epiaristolochene and epieremophilene are hydroxylated at C-2 to give a 2β-hydroxy derivatives that are not oxidized further. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
| References: |
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