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Your query returned 3 entries. Printable version
EC | 2.8.3.22 | ||||||||||||
Accepted name: | succinyl-CoA—L-malate CoA-transferase | ||||||||||||
Reaction: | (1) succinyl-CoA + (S)-malate = succinate + (S)-malyl-CoA (2) succinyl-CoA + (S)-citramalate = succinate + (S)-citramalyl-CoA |
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For diagram of the 3-hydroxypropanoate cycle, click here | |||||||||||||
Glossary: | (S)-citramalate = (2S)-2-hydroxy-2-methylbutanedioate (S)-malate = (2S)-2-hydroxybutanedioate (S)-malyl-CoA = (3S)-3-carboxy-3-hydroxypropanoyl-CoA |
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Other name(s): | SmtAB | ||||||||||||
Systematic name: | succinyl-CoA:(S)-malate CoA-transferase | ||||||||||||
Comments: | The enzyme, purified from the bacterium Chloroflexus aurantiacus, can also accept itaconate as acceptor, with lower efficiency. It is part of the 3-hydroxypropanoate cycle for carbon assimilation. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||
References: |
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EC | 3.1.2.30 | ||||||||||||
Accepted name: | (3S)-malyl-CoA thioesterase | ||||||||||||
Reaction: | (S)-malyl-CoA + H2O = (S)-malate + CoA | ||||||||||||
Glossary: | (S)-malate = (2S)-2-hydroxybutanedioate (S)-malyl-CoA = (3S)-3-carboxy-3-hydroxypropanoyl-CoA |
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Other name(s): | mcl2 (gene name) | ||||||||||||
Systematic name: | (S)-malyl-CoA hydrolase | ||||||||||||
Comments: | Stimulated by Mg2+ or Mn2+. The enzyme has no activity with (2R,3S)-2-methylmalyl-CoA (cf. EC 4.1.3.24, malyl-CoA lyase) or other CoA esters. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||
References: |
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EC | 4.1.3.24 | ||||||||||||
Accepted name: | malyl-CoA lyase | ||||||||||||
Reaction: | (1) (S)-malyl-CoA = acetyl-CoA + glyoxylate (2) (2R,3S)-2-methylmalyl-CoA = propanoyl-CoA + glyoxylate |
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For diagram of the 3-hydroxypropanoate cycle, click here | |||||||||||||
Glossary: | (S)-malyl-CoA = (3S)-3-carboxy-3-hydroxypropanoyl-CoA (2R,3S)-2-methylmalyl-CoA = L-erythro-β-methylmalyl-CoA = (2R,3S)-2-methyl-3-carboxy-3-hydroxypropanoyl-CoA |
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Other name(s): | malyl-coenzyme A lyase; (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase; mclA (gene name); mcl1 (gene name); (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming); L-malyl-CoA lyase | ||||||||||||
Systematic name: | (S)-malyl-CoA glyoxylate-lyase (acetyl-CoA-forming) | ||||||||||||
Comments: | The enzymes from Rhodobacter species catalyse a step in the ethylmalonyl-CoA pathway for acetate assimilation [3,5]. The enzyme from halophilic bacteria participate in the methylaspartate cycle and catalyse the reaction in the direction of malyl-CoA formation [6]. The enzyme from the bacterium Chloroflexus aurantiacus, which participates in the 3-hydroxypropanoate cycle for carbon assimilation, also has the activity of EC 4.1.3.25, (3S)-citramalyl-CoA lyase [2,4]. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 37290-67-8 | ||||||||||||
References: |
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