The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 1.14.14.171     
Accepted name: β-amyrin 16α-hydroxylase
Reaction: β-amyrin + [reduced NADPH—hemoprotein reductase] + O2 = 16α-hydroxy-β-amyrin + [oxidized NADPH—hemoprotein reductase] + H2O
Glossary: 16α-hydroxy-β-amyrin = olean-12-ene-3β,16α-diol
Other name(s): CYP87D16
Systematic name: β-amyrin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (16α-hydroxylating)
Comments: A cytochrome P-450 (heme-thiolate) protein isolated from the plant Maesa lanceolata (false assegai). Involved in the biosynthesis of maesasaponins. It also acts on some derivatives of β-amyrin such as erythrodiol or oleanolic acid.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Moses, T., Pollier, J., Almagro, L., Buyst, D., Van Montagu, M., Pedreño, M.A., Martins, J.C., Thevelein, J.M. and Goossens, A. Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum. Proc. Natl. Acad. Sci. USA 111 (2014) 1634–1639. [PMID: 24434554]
2.  Moses, T., Pollier, J., Faizal, A., Apers, S., Pieters, L., Thevelein, J.M., Geelen, D. and Goossens, A. Unraveling the triterpenoid saponin biosynthesis of the African shrub Maesa lanceolata. Mol. Plant 8 (2015) 122–135. [DOI] [PMID: 25578277]
[EC 1.14.14.171 created 2019]
 
 


Data © 2001–2020 IUBMB
Web site © 2005–2020 Andrew McDonald