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Your query returned 13 entries. Printable version
EC | 1.3.8.15 | ||||||
Accepted name: | 3-(aryl)acrylate reductase | ||||||
Reaction: | (1) phloretate + electron-transfer flavoprotein = 4-coumarate + reduced electron-transfer flavoprotein (2) 3-phenylpropanoate + electron-transfer flavoprotein = trans-cinnamate + reduced electron-transfer flavoprotein (3) 3-(1H-indol-3-yl)propanoate + electron-transfer flavoprotein = 3-(indol-3-yl)acrylate + reduced electron-transfer flavoprotein |
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Glossary: | phloretate = 3-(4-hydroxyphenyl)propanoate crotonate = (2E)-but-2-enoate |
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Other name(s): | acdA (gene name) | ||||||
Systematic name: | 3-(phenyl)propanoate:electron-transfer flavoprotein 2,3-oxidoreductase | ||||||
Comments: | The enzyme, found in some amino acid-fermenting anaerobic bacteria, participates in the fermentation pathways of L-phenylalanine, L-tyrosine, and L-tryptophan. Unlike EC 1.3.1.31, 2-enoate reductase, this enzyme has minimal activity with crotonate. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
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EC | 1.14.13.21 | ||||||
Transferred entry: | flavonoid 3′-monooxygenase. Now EC 1.14.14.82, flavonoid 3′-monooxygenase. | ||||||
EC | 1.14.14.82 | ||||||
Accepted name: | flavonoid 3′-monooxygenase | ||||||
Reaction: | a flavonoid + [reduced NADPH—hemoprotein reductase] + O2 = a 3′-hydroxyflavonoid + [oxidized NADPH—hemoprotein reductase] + H2O | ||||||
For diagram of flavonoid biosynthesis, click here and for diagram of the biosynthesis of naringenin derivatives, click here | |||||||
Other name(s): | CYP75B1 (gene name); flavonoid 3′-hydroxylase; flavonoid 3-hydroxylase (incorrect); NADPH:flavonoid-3′-hydroxylase (incorrect); flavonoid 3-monooxygenase (incorrect) | ||||||
Systematic name: | flavonoid,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (3′-hydroxylating) | ||||||
Comments: | A cytochrome P-450 (heme-thiolate) protein found in plants. Acts on a number of flavonoids, including the flavanone naringenin and the flavone apigenin. Does not act on 4-coumarate or 4-coumaroyl-CoA. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 75991-44-5 | ||||||
References: |
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EC | 1.14.17.2 | ||||||
Deleted entry: | 4-coumarate 3-monooxygenase. Now included with EC 1.14.18.1 monophenol monooxygenase | ||||||
EC | 2.4.1.120 | ||||||
Accepted name: | sinapate 1-glucosyltransferase | ||||||
Reaction: | UDP-α-D-glucose + sinapate = UDP + 1-O-sinapoyl-β-D-glucose | ||||||
Glossary: | sinapate = (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate | ||||||
Other name(s): | uridine diphosphoglucose-sinapate glucosyltransferase; UDP-glucose:sinapic acid glucosyltransferase; uridine 5′-diphosphoglucose-hydroxycinnamic acid acylglucosyltransferase; UDP-glucose:sinapate D-glucosyltransferase | ||||||
Systematic name: | UDP-α-D-glucose:sinapate D-glucosyltransferase | ||||||
Comments: | Some other hydroxycinnamates, including 4-coumarate, ferulate and caffeate, can act as acceptors, but more slowly. Only glucose esters, not glucosides, are formed (cf. EC 2.4.1.126 hydroxycinnamate 4-β-glucosyltransferase). | ||||||
Links to other databases: | BRENDA, EXPASY, GTD, KEGG, MetaCyc, CAS registry number: 74082-53-4 | ||||||
References: |
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EC | 2.4.1.126 | ||||||
Accepted name: | hydroxycinnamate 4-β-glucosyltransferase | ||||||
Reaction: | UDP-glucose + trans-4-hydroxycinnamate = UDP + 4-O-β-D-glucosyl-4-hydroxycinnamate | ||||||
Other name(s): | uridine diphosphoglucose-hydroxycinnamate glucosyltransferase; UDP-glucose-hydroxycinnamate glucosyltransferase; hydroxycinnamoyl glucosyltransferase | ||||||
Systematic name: | UDP-glucose:trans-4-hydroxycinnamate 4-O-β-D-glucosyltransferase | ||||||
Comments: | Acts on 4-coumarate, ferulate, caffeate and sinapate, forming a mixture of 4-glucosides and glucose esters (cf. EC 2.4.1.120 sinapate 1-glucosyltransferase). | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 77848-85-2 | ||||||
References: |
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EC | 2.4.1.177 | ||||||
Accepted name: | cinnamate β-D-glucosyltransferase | ||||||
Reaction: | UDP-glucose + trans-cinnamate = UDP + trans-cinnamoyl β-D-glucoside | ||||||
Other name(s): | uridine diphosphoglucose-cinnamate glucosyltransferase; UDPG:t-cinnamate glucosyltransferase | ||||||
Systematic name: | UDP-glucose:trans-cinnamate β-D-glucosyltransferase | ||||||
Comments: | 4-Coumarate, 2-coumarate, benzoate, feruloate and caffeate can also act as acceptors, but more slowly. Involved in the biosynthesis of chlorogenic acid in the root of the sweet potato, Ipomoea batatas. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 83744-95-0 | ||||||
References: |
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EC | 2.4.1.271 | ||||||
Accepted name: | crocetin glucosyltransferase | ||||||
Reaction: | (1) UDP-α-D-glucose + crocetin = UDP + β-D-glucosyl crocetin (2) UDP-α-D-glucose + β-D-glucosyl crocetin = UDP + bis(β-D-glucosyl) crocetin (3) UDP-α-D-glucose + β-D-gentiobiosyl crocetin = UDP + β-D-gentiobiosyl β-D-glucosyl crocetin |
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For diagram of crocin biosynthesis, click here | |||||||
Other name(s): | crocetin GTase; UGTCs2; UGT75L6; UDP-glucose:crocetin glucosyltransferase; UDP-glucose:crocetin 8-O-D-glucosyltransferase | ||||||
Systematic name: | UDP-α-D-glucose:crocetin 8-O-D-glucosyltransferase | ||||||
Comments: | In the plants Crocus sativus and Gardenia jasminoides this enzyme esterifies a free carboxyl group of crocetin and some crocetin glycosyl esters. The enzyme from Gardenia can also form glucosyl esters with 4-coumarate, caffeate and ferulate [3]. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
References: |
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EC | 2.8.3.17 | ||||||
Accepted name: | 3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase | ||||||
Reaction: | (1) (E)-cinnamoyl-CoA + (R)-(phenyl)lactate = (E)-cinnamate + (R)-(phenyl)lactoyl-CoA (2) (E)-4-coumaroyl-CoA + (R)-3-(4-hydroxyphenyl)lactate = 4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA (3) 3-(indol-3-yl)acryloyl-CoA + (R)-3-(indol-3-yl)lactate = 3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA |
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Other name(s): | FldA; cinnamoyl-CoA:phenyllactate CoA-transferase | ||||||
Systematic name: | 3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase | ||||||
Comments: | The enzyme, found in some amino acid-fermenting anaerobic bacteria, participates in the fermentation pathways of L-phenylalanine, L-tyrosine, and L-tryptophan. It forms a complex with EC 4.2.1.175, (R)-3-(aryl)lactoyl-CoA dehydratase. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 289682-21-9 | ||||||
References: |
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EC | 2.8.3.23 | ||||||
Accepted name: | caffeate CoA-transferase | ||||||
Reaction: | 3-(3,4-dihydroxyphenyl)propanoyl-CoA + (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate = 3-(3,4-dihydroxyphenyl)propanoate + (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl-CoA | ||||||
Glossary: | 3-(3,4-dihydroxyphenyl)propanoate = hydrocaffeate (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate = (2E)-3-(3,4-dihydroxyphenyl)acrylate = trans-caffeate |
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Other name(s): | CarA | ||||||
Systematic name: | 3-(3,4-dihydroxyphenyl)propanoyl-CoA:(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate CoA-transferase | ||||||
Comments: | The enzyme, isolated from the bacterium Acetobacterium woodii, catalyses an energy-saving CoA loop for caffeate activation. In addition to caffeate, the enzyme can utilize 4-coumarate or ferulate as CoA acceptor. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
References: |
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EC | 4.1.1.102 | ||||||
Accepted name: | phenacrylate decarboxylase | ||||||
Reaction: | (1) 4-coumarate = 4-vinylphenol + CO2 (2) trans-cinnamate = styrene + CO2 (3) ferulate = 4-vinylguaiacol + CO2 |
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Glossary: | 4-coumarate = 3-(4-hydroxyphenyl)prop-2-enoate trans-cinnamate = (2E)-3-phenylprop-2-enoate ferulate = 4-hydroxy-3-methoxycinnamate |
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Other name(s): | FDC1 (gene name); ferulic acid decarboxylase | ||||||
Systematic name: | 3-phenylprop-2-enoate carboxy-lyase | ||||||
Comments: | The enzyme, found in fungi, catalyses the decarboxylation of phenacrylic acids present in plant cell walls. It requires a prenylated flavin cofactor that is produced by EC 2.5.1.129, flavin prenyltransferase. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||
References: |
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EC | 4.1.2.66 | ||||||
Accepted name: | 4-coumarate hydratase/lyase | ||||||
Reaction: | 4-coumarate + H2O = 4-hydroxybenzaldehyde + acetate (overall reaction) (1a) 4-coumarate + H2O = 3-hydroxy-3-(4-hydroxyphenyl)propanoate (1b) 3-hydroxy-3-(4-hydroxyphenyl)propanoate = 4-hydroxybenzaldehyde + acetate |
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Glossary: | 4-coumarate = (2E)-3-(4-hydroxyphenyl)acrylate = (2E)-3-(4-hydroxyphenyl)prop-2-enoate | ||||||
Other name(s): | 4-hydroxybenzaldehyde synthase; 4HBS | ||||||
Systematic name: | 4-coumarate acetate-lyase (4-hydroxybenzaldehyde-forming) | ||||||
Comments: | The enzyme has been purified from vanilla pods of the orchid Vanilla planifolia. It is highly specific for 4-coumarate. Similar compounds such as cinnamate, caffeate, sinapate and o-coumarate are not substrates. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
References: |
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EC | 6.2.1.12 | ||||||
Accepted name: | 4-coumarate—CoA ligase | ||||||
Reaction: | ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA | ||||||
For diagram of chalcone and stilbene biosynthesis, click here | |||||||
Glossary: | 4-coumarate = 3-(4-hydroxyphenyl)prop-2-enoate | ||||||
Other name(s): | 4-coumaroyl-CoA synthetase; p-coumaroyl CoA ligase; p-coumaryl coenzyme A synthetase; p-coumaryl-CoA synthetase; p-coumaryl-CoA ligase; feruloyl CoA ligase; hydroxycinnamoyl CoA synthetase; 4-coumarate:coenzyme A ligase; caffeolyl coenzyme A synthetase; p-hydroxycinnamoyl coenzyme A synthetase; feruloyl coenzyme A synthetase; sinapoyl coenzyme A synthetase; 4-coumaryl-CoA synthetase; hydroxycinnamate:CoA ligase; p-coumaryl-CoA ligase; p-hydroxycinnamic acid:CoA ligase; 4CL | ||||||
Systematic name: | 4-coumarate:CoA ligase (AMP-forming) | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37332-51-7 | ||||||
References: |
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