EC |
4.2.3.170 |
Accepted name: |
4-epi-cubebol synthase |
Reaction: |
(2E,6E)-farnesyl diphosphate + H2O = 4-epi-cubebol + diphosphate |
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For diagram of ent-cadinane sesquiterpenoid biosynthesis, click here |
Glossary: |
4-epi-cubebol = (3S,3aS,3bR,4S,7S,7aS)-4-(2-hydroxypropan-2-yl)-7-methyloctahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzen-3-ol |
Systematic name: |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 4-epi-cubebol-forming) |
Comments: |
The enzyme, found in the bacterium Streptosporangium roseum, is specific for (2E,6E)-farnesyl diphosphate. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Rabe, P., Schmitz, T. and Dickschat, J.S. Mechanistic investigations on six bacterial terpene cyclases. Beilstein J. Org. Chem. 12 (2016) 1839–1850. [DOI] [PMID: 27829890] |
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[EC 4.2.3.170 created 2017] |
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