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Your query returned 4 entries. Printable version
EC | 1.21.98.1 | ||||||||||||||
Accepted name: | cyclic dehypoxanthinyl futalosine synthase | ||||||||||||||
Reaction: | dehypoxanthine futalosine + S-adenosyl-L-methionine = cyclic dehypoxanthinyl futalosine + 5′-deoxyadenosine + L-methionine | ||||||||||||||
For diagram of the futalosine pathway, click here | |||||||||||||||
Glossary: | dehypoxanthine futalosine = 3-{3-[(2R,3S,4R)-3,4,5-trihydroxytetrahydrofuran-2-yl]propanoyl}benzoate cyclic dehypoxanthinyl futalosine = (2R,3S,4R)-3,4,5-trihydroxy-4′-oxo-3′,4,4′,5-tetrahydro-2’H,3H-spiro[furan-2,1′-naphthalene]-6′-carboxylate |
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Other name(s): | MqnC; dehypoxanthinyl futalosine cyclase | ||||||||||||||
Systematic name: | dehypoxanthine futalosine:S-adenosyl-L-methionine oxidoreductase (cyclizing) | ||||||||||||||
Comments: | This enzyme is a member of the AdoMet radical (radical SAM) family. The enzyme, found in several bacterial species, is part of the futalosine pathway for menaquinone biosynthesis. | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||||
References: |
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EC | 1.21.99.2 | ||||||||||||||
Transferred entry: | EC 1.21.99.2, cyclic dehypoxanthinyl futalosine synthase. Now classified as EC 1.21.98.1, cyclic dehypoxanthinyl futalosine synthase. | ||||||||||||||
EC | 3.2.2.26 | ||||||||||||||
Accepted name: | futalosine hydrolase | ||||||||||||||
Reaction: | futalosine + H2O = dehypoxanthine futalosine + hypoxanthine | ||||||||||||||
For diagram of the futalosine pathway, click here | |||||||||||||||
Glossary: | futalosine = 3-(3-((3S,4R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9(6H)-yl)tetrahydrofuran-2-yl)propanoyl)benzoate dehypoxanthine futalosine = 7-(3-carboxyphenyl)-D-ribo-7-dehydro-5,6-dideoxyheptose |
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Other name(s): | futalosine nucleosidase; MqnB (ambiguous) | ||||||||||||||
Systematic name: | futalosine ribohydrolase | ||||||||||||||
Comments: | This enzyme, which is specific for futalosine, catalyses the second step of a novel menaquinone biosynthetic pathway that is found in some prokaryotes. | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||||
References: |
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EC | 3.2.2.30 | ||||||||||||||
Accepted name: | aminodeoxyfutalosine nucleosidase | ||||||||||||||
Reaction: | 6-amino-6-deoxyfutalosine + H2O = dehypoxanthine futalosine + adenine | ||||||||||||||
For diagram of the futalosine pathway, click here | |||||||||||||||
Glossary: | 6-amino-6-deoxyfutalosine = 3-{3-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]propanoyl}benzoate dehypoxanthine futalosine = 3-{3-[(2R,3S,4R)-3,4,5-trihydroxytetrahydrofuran-2-yl]propanoyl}benzoate |
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Other name(s): | AFL nucleosidase; aminofutalosine nucleosidase; methylthioadenosine nucleosidase; MqnB (ambiguous) | ||||||||||||||
Systematic name: | 6-amino-6-deoxyfutalosine ribohydrolase | ||||||||||||||
Comments: | The enzyme, found in several bacterial species, catalyses a step in a modified futalosine pathway for menaquinone biosynthesis. While the enzyme from some organisms also has the activity of EC 3.2.2.9, adenosylhomocysteine nucleosidase, the enzyme from Chlamydia trachomatis is specific for 6-amino-6-deoxyfutalosine [7]. | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||||
References: |
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