The Enzyme Database

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EC 1.14.14.72     
Accepted name: drimenol monooxygenase
Reaction: drimenol + [reduced NADPH—hemoprotein reductase] + O2 = drimendiol + [oxidized NADPH—hemoprotein reductase] + H2O
For diagram of podophyllotoxin biosynthesis, click here and for diagram of drimenol metabolites, click here
Glossary: drimendiol = drim-7-ene-11,12-diol
Other name(s): PhDOX1
Systematic name: drimenol,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (drimendiol-forming)
Comments: A cytochrome P-450 (heme-thiolate) protein isolated from the plant Persicaria hydropiper (water pepper).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Henquet, M.GL., Prota, N., van der Hooft, J.JJ., Varbanova-Herde, M., Hulzink, R.JM., de Vos, M., Prins, M., de Both, M.TJ., Franssen, M.CR., Bouwmeester, H. and Jongsma, M. Identification of a drimenol synthase and drimenol oxidase from Persicaria hydropiper, involved in the biosynthesis of insect deterrent drimanes. Plant J. 90 (2017) 1052–1063. [DOI] [PMID: 28258968]
[EC 1.14.14.72 created 2018]
 
 


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