The Enzyme Database

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EC 2.1.4.3     
Accepted name: L-arginine:L-lysine amidinotransferase
Reaction: L-arginine + L-lysine = L-ornithine + L-homoarginine
Glossary: phaseolotoxin = N5-[amino(sulfoamino)phosphoryl]-L-ornithyl-L-alanyl-L-arginine
Other name(s): amtA (gene name)
Systematic name: L-arginine:L-lysine amidinotransferase
Comments: The enzyme, characterized from the bacterium Pseudomonas savastanoi pv. phaseolicola, is involved in the biosynthesis of the toxin phaseolotoxin, a modified tripeptide that causes the ’halo blight’ disease of beans.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Hernandez-Guzman, G. and Alvarez-Morales, A. Isolation and characterization of the gene coding for the amidinotransferase involved in the biosynthesis of phaseolotoxin in Pseudomonas syringae pv. phaseolicola. Mol. Plant Microbe Interact. 14 (2001) 545–554. [PMID: 11310742]
2.  Li, M., Chen, L., Deng, Z. and Zhao, C. Characterization of AmtA, an amidinotransferase involved in the biosynthesis of phaseolotoxins. FEBS Open Bio 6 (2016) 603–609. [PMID: 27419063]
[EC 2.1.4.3 created 2019]
 
 


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