|
Your query returned 3 entries. Printable version
EC | 1.14.13.103 | ||||
Transferred entry: | 8-dimethylallylnaringenin 2-hydroxylase. Now EC 1.14.14.142, 8-dimethylallylnaringenin 2-hydroxylase | ||||
EC | 1.14.14.142 | ||||
Accepted name: | 8-dimethylallylnaringenin 2′-hydroxylase | ||||
Reaction: | sophoraflavanone B + [reduced NADPH—hemoprotein reductase] + O2 = leachianone G + [oxidized NADPH—hemoprotein reductase] + H2O | ||||
For diagram of sophoraflavanone G biosynthesis, click here | |||||
Glossary: | dimethylallyl = prenyl = 3-methylbut-2-en-1-yl lavandulyl = 5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl leachianone G = (–)-(2S)-2′-hydroxy-8-prenylnaringenin = (–)-(2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one naringenin = 5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one sophoraflavanone B = (–)-(2S)-8-prenylnaringenin = (–)-(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one |
||||
Other name(s): | 8-DMAN 2′-hydroxylase | ||||
Systematic name: | sophoraflavanone-B,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (2′-hydroxylating) | ||||
Comments: | A membrane-bound cytochrome P-450 (heme-thiolate) protein that is associated with the endoplasmic reticulum [1,2]. This enzyme is specific for sophoraflavanone B as substrate. Along with EC 2.5.1.70 (naringenin 8-dimethylallyltransferase) and EC 2.5.1.71 (leachianone G 2′′-dimethylallyltransferase), this enzyme forms part of the sophoraflavanone G biosynthetic pathway. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
References: |
| ||||
EC | 2.5.1.70 | ||||
Accepted name: | naringenin 8-dimethylallyltransferase | ||||
Reaction: | prenyl diphosphate + (–)-(2S)-naringenin = diphosphate + sophoraflavanone B | ||||
For diagram of sophoraflavanone G biosynthesis, click here | |||||
Glossary: | dimethylallyl = prenyl = 3-methylbut-2-en-1-yl (–)-(2S)-naringenin = (–)-(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one sophoraflavanone B = (–)-(2S)-8-prenylnaringenin = (–)-(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-2,3-dihydrochromen-4-one |
||||
Other name(s): | N8DT; dimethylallyl-diphosphate:naringenin 8-dimethylallyltransferase | ||||
Systematic name: | prenyl-diphosphate:naringenin 8-prenyltransferase | ||||
Comments: | Requires Mg2+. This membrane-bound protein is located in the plastids [2]. In addition to naringenin, the enzyme can prenylate several other flavanones at the C-8 position, but more slowly. Along with EC 1.14.14.142 (8-dimethylallylnaringenin 2′-hydroxylase) and EC 2.5.1.71 (leachianone-G 2′′-dimethylallyltransferase), this enzyme forms part of the sophoraflavanone-G-biosynthesis pathway. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
References: |
| ||||