Canadine biosynthesis

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scoulerine to tetrahydrocolumbamine biosynthesis
EC 1.3.3.8 tetrahydroberberine oxidase
EC 1.5.1.31 berberine reductase
EC 1.14.13.37 see EC 1.14.14.97
EC 1.14.14.97 methyltetrahydroprotoberberine 14-monooxygenase
EC 1.14.19.68 (S)-canadine synthase
EC 1.14.21.5 see EC 1.14.19.68
EC 2.1.1.122 (S)-tetrahydroprotoberberine N-methyltransferase