The Enzyme Database

Table of Contents

The enzymes in this section of the database are organized as you would find them in the Enzyme-Nomenclature book. Click [+] to expand, and [–] to collapse, any section. Clicking on a heading will open a popup window with information on that class, subclass or sub-subclass.

For a fully expanded list of the classes, subclasses and sub-subclasses, click here

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EC 1 [+]   
EC 2 []   
    EC 2.1  []      
        EC 2.1.1       []    Methyltransferases 
                EC 2.1.1.1                      nicotinamide N-methyltransferase 
                EC 2.1.1.2                      guanidinoacetate N-methyltransferase 
                EC 2.1.1.3                      thetin—homocysteine S-methyltransferase 
                EC 2.1.1.4                      acetylserotonin O-methyltransferase 
                EC 2.1.1.5                      betaine—homocysteine S-methyltransferase 
                EC 2.1.1.6                      catechol O-methyltransferase 
                EC 2.1.1.7                      nicotinate N-methyltransferase 
                EC 2.1.1.8                      histamine N-methyltransferase 
                EC 2.1.1.9                      thiol S-methyltransferase 
                EC 2.1.1.10                      homocysteine S-methyltransferase 
                EC 2.1.1.11                      magnesium protoporphyrin IX methyltransferase 
                EC 2.1.1.12                      methionine S-methyltransferase 
                EC 2.1.1.13                      methionine synthase 
                EC 2.1.1.14                      5-methyltetrahydropteroyltriglutamate—homocysteine S-methyltransferase 
                EC 2.1.1.15                      fatty-acid O-methyltransferase 
                EC 2.1.1.16                      methylene-fatty-acyl-phospholipid synthase 
                EC 2.1.1.17                      phosphatidylethanolamine N-methyltransferase 
                EC 2.1.1.18                      polysaccharide O-methyltransferase 
                EC 2.1.1.19                      trimethylsulfonium—tetrahydrofolate N-methyltransferase 
                EC 2.1.1.20                      glycine N-methyltransferase 
                EC 2.1.1.21                      methylamine—glutamate N-methyltransferase 
                EC 2.1.1.22                      carnosine N-methyltransferase 
                EC 2.1.1.23                       protein-arginine N-methyltransferase. Now listed as EC 2.1.1.124 [cytochrome c]-arginine N-methyltransferase, EC 2.1.1.125 histone-arginine N-methyltransferase and EC 2.1.1.126 [myelin basic protein]-arginine N-methyltransferase 
                EC 2.1.1.24                       protein-γ-glutamate O-methyltransferase. Now listed as EC 2.1.1.77 protein-L-isoaspartate(D-aspartate) O-methyltransferase, EC 2.1.1.80 protein-glutamate O-methyltransferase and EC 2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase 
                EC 2.1.1.25                      phenol O-methyltransferase 
                EC 2.1.1.26                      iodophenol O-methyltransferase 
                EC 2.1.1.27                      tyramine N-methyltransferase 
                EC 2.1.1.28                      phenylethanolamine N-methyltransferase 
                EC 2.1.1.29                      tRNA (cytosine-5-)-methyltransferase. Now covered by EC 2.1.1.202 [multisite-specific tRNA:(cytosine-C5)-methyltransferase], EC 2.1.1.203 [tRNA (cytosine34-C5)-methyltransferase] and EC 2.1.1.204 [RNA (cytosine38-C5)-methyltransferase]. 
                EC 2.1.1.30                      tRNA (purine-2- or -6-)-methyltransferase. Reactions previously described are due to EC 2.1.1.32 tRNA (guanine-N2-)-methyltransferase 
                EC 2.1.1.31                      tRNA (guanine-N1-)-methyltransferase. Now covered by EC 2.1.1.221 (tRNA (guanine9-N1)-methyltransferase) and EC 2.1.1.228 (tRNA (guanine37-N1)-methyltransferase). 
                EC 2.1.1.32                      tRNA (guanine-N2-)-methyltransferase. Now covered by EC 2.1.1.213 [tRNA (guanine10-N2)-dimethyltransferase], EC 2.1.1.214 [tRNA (guanine10-N2)-monomethyltransferase], EC 2.1.1.215 [tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase] and EC 2.1.1.216 [tRNA (guanine26-N2)-dimethyltransferase] 
                EC 2.1.1.33                      tRNA (guanine46-N7)-methyltransferase 
                EC 2.1.1.34                      tRNA (guanosine18-2′-O)-methyltransferase 
                EC 2.1.1.35                      tRNA (uracil54-C5)-methyltransferase 
                EC 2.1.1.36                      tRNA (adenine-N1-)-methyltransferase. Now covered by EC 2.1.1.217 (tRNA (adenine22-N1)-methyltransferase), EC 2.1.1.218 (tRNA (adenine9-N1)-methyltransferase), EC 2.1.1.219 (tRNA (adenine57-N1/adenine58-N1)-methyltransferase), EC 2.1.1.220 (tRNA (adenine58-N1)-methyltransferase). 
                EC 2.1.1.37                      DNA (cytosine-5-)-methyltransferase 
                EC 2.1.1.38                      O-demethylpuromycin O-methyltransferase 
                EC 2.1.1.39                      inositol 3-methyltransferase 
                EC 2.1.1.40                      inositol 1-methyltransferase 
                EC 2.1.1.41                      sterol 24-C-methyltransferase 
                EC 2.1.1.42                      flavone 3′-O-methyltransferase 
                EC 2.1.1.43                      histone-lysine N-methyltransferase. Now described by EC 2.1.1.354, [histone H3]-lysine4 N-trimethyltransferase; EC 2.1.1.355, [histone H3]-lysine9 N-trimethyltransferase; EC 2.1.1.356, [histone H3]-lysine27 N-trimethyltransferase; EC 2.1.1.357, [histone H3]-lysine36 N-dimethyltransferase; EC 2.1.1.358, [histone H3]-dimethyl-L-lysine36 N-methyltransferase; EC 2.1.1.359, [histone H3]-lysine36 N-trimethyltransferase; EC 2.1.1.360, [histone H3]-lysine79 N-trimethyltransferase; EC 2.1.1.361, [histone H4]-lysine20 N-methyltransferase, and EC 2.1.1.362, [histone H4]-N-methyl-L-lysine20 N-methyltransferase. 
                EC 2.1.1.44                      L-histidine Nα-methyltransferase 
                EC 2.1.1.45                      thymidylate synthase 
                EC 2.1.1.46                      isoflavone 4′-O-methyltransferase 
                EC 2.1.1.47                      indolepyruvate C-methyltransferase 
                EC 2.1.1.48                      rRNA (adenine-N6-)-methyltransferase. Now covered by EC 2.1.1.181 [23S rRNA (adenine1618-N6)-methyltransferase], EC 2.1.1.182 [16S rRNA adenine1518-N6/adenine1519-N6)-dimethyltransferase], EC 2.1.1.183 [18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase] and EC 2.1.1.184 [23S rRNA (adenine2085-N6)-dimethyltransferase] 
                EC 2.1.1.49                      amine N-methyltransferase 
                EC 2.1.1.50                      loganate O-methyltransferase 
                EC 2.1.1.51                      rRNA (guanine-N1-)-methyltransferase. Now covered by EC 2.1.1.187 [23S rRNA (guanine745-N1)-methyltransferase] and EC 2.1.1.188 [23S rRNA (guanine748-N1)-methyltransferase]. 
                EC 2.1.1.52                      rRNA (guanine-N2-)-methyltransferase. Now covered by EC 2.1.1.171 [16S rRNA (guanine966-N2)-methyltransferase], EC 2.1.1.172 [16S rRNA (guanine1207-N2)-methyltransferase], EC 2.1.1.173 [23S rRNA (guanine2445-N2)-methyltransferase] and EC 2.1.1.174 [23S rRNA (guanine1835-N2)-methyltransferase] 
                EC 2.1.1.53                      putrescine N-methyltransferase 
                EC 2.1.1.54                      deoxycytidylate C-methyltransferase 
                EC 2.1.1.55                      tRNA (adenine-N6-)-methyltransferase 
                EC 2.1.1.56                      mRNA (guanine-N7)-methyltransferase 
                EC 2.1.1.57                      methyltransferase cap1 
                EC 2.1.1.58                      mRNA (adenosine-2′-O-)-methyltransferase. Now included with EC 2.1.1.57, mRNA (nucleoside-2′-O-)-methyltransferase 
                EC 2.1.1.59                      [cytochrome c]-lysine N-methyltransferase 
                EC 2.1.1.60                      calmodulin-lysine N-methyltransferase 
                EC 2.1.1.61                      tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase 
                EC 2.1.1.62                      mRNA (2′-O-methyladenosine-N6-)-methyltransferase 
                EC 2.1.1.63                      methylated-DNA—[protein]-cysteine S-methyltransferase 
                EC 2.1.1.64                      3-demethylubiquinol 3-O-methyltransferase 
                EC 2.1.1.65                      licodione 2′-O-methyltransferase 
                EC 2.1.1.66                      rRNA (adenosine-2′-O-)-methyltransferase. Now covered by EC 2.1.1.230, 23S rRNA (adenosine1067-2-O)-methyltransferase. 
                EC 2.1.1.67                      thiopurine S-methyltransferase 
                EC 2.1.1.68                      caffeate O-methyltransferase 
                EC 2.1.1.69                      5-hydroxyfuranocoumarin 5-O-methyltransferase 
                EC 2.1.1.70                      8-hydroxyfuranocoumarin 8-O-methyltransferase 
                EC 2.1.1.71                      phosphatidyl-N-methylethanolamine N-methyltransferase 
                EC 2.1.1.72                      site-specific DNA-methyltransferase (adenine-specific) 
                EC 2.1.1.73                       site-specific DNA-methyltransferase (cytosine-specific). Reaction is that of EC 2.1.1.37, DNA (cytosine-5-)-methyltransferase 
                EC 2.1.1.74                      methylenetetrahydrofolate—tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing] 
                EC 2.1.1.75                      apigenin 4′-O-methyltransferase 
                EC 2.1.1.76                      quercetin 3-O-methyltransferase 
                EC 2.1.1.77                      protein-L-isoaspartate(D-aspartate) O-methyltransferase 
                EC 2.1.1.78                      isoorientin 3′-O-methyltransferase 
                EC 2.1.1.79                      cyclopropane-fatty-acyl-phospholipid synthase 
                EC 2.1.1.80                      protein-glutamate O-methyltransferase 
                EC 2.1.1.81                       nicotine N-methyltransferase. Now included with EC 2.1.1.49 amine N-methyltransferase 
                EC 2.1.1.82                      3-methylquercetin 7-O-methyltransferase 
                EC 2.1.1.83                      3,7-dimethylquercetin 4′-O-methyltransferase 
                EC 2.1.1.84                      methylquercetagetin 6-O-methyltransferase 
                EC 2.1.1.85                      protein-histidine N-methyltransferase 
                EC 2.1.1.86                      tetrahydromethanopterin S-methyltransferase. Now EC 7.2.1.4, tetrahydromethanopterin S-methyltransferase 
                EC 2.1.1.87                      pyridine N-methyltransferase 
                EC 2.1.1.88                      8-hydroxyquercetin 8-O-methyltransferase 
                EC 2.1.1.89                      tetrahydrocolumbamine 2-O-methyltransferase 
                EC 2.1.1.90                      methanol—corrinoid protein Co-methyltransferase 
                EC 2.1.1.91                      isobutyraldoxime O-methyltransferase 
                EC 2.1.1.92                      bergaptol O-methyltransferase. Now included with EC 2.1.1.69, 5-hydroxyfuranocoumarin 5-O-methyltransferase. The reaction with bergaptol is a specific example of the general reaction associated with EC 2.1.1.69 
                EC 2.1.1.93                      xanthotoxol O-methyltransferase. Enzyme is identical to EC 2.1.1.70, 8-hydroxyfuranocoumarin 8-O-methyltransferase 
                EC 2.1.1.94                      tabersonine 16-O-methyltransferase 
                EC 2.1.1.95                      tocopherol C-methyltransferase 
                EC 2.1.1.96                      thioether S-methyltransferase 
                EC 2.1.1.97                      3-hydroxyanthranilate 4-C-methyltransferase 
                EC 2.1.1.98                      diphthine synthase 
                EC 2.1.1.99                      3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase 
                EC 2.1.1.100                      protein-S-isoprenylcysteine O-methyltransferase 
                EC 2.1.1.101                      macrocin O-methyltransferase 
                EC 2.1.1.102                      demethylmacrocin O-methyltransferase 
                EC 2.1.1.103                      phosphoethanolamine N-methyltransferase 
                EC 2.1.1.104                      caffeoyl-CoA O-methyltransferase 
                EC 2.1.1.105                      N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase 
                EC 2.1.1.106                      tryptophan 2-C-methyltransferase 
                EC 2.1.1.107                      uroporphyrinogen-III C-methyltransferase 
                EC 2.1.1.108                      6-hydroxymellein O-methyltransferase 
                EC 2.1.1.109                      demethylsterigmatocystin 6-O-methyltransferase 
                EC 2.1.1.110                      sterigmatocystin 8-O-methyltransferase 
                EC 2.1.1.111                      anthranilate N-methyltransferase 
                EC 2.1.1.112                      glucuronoxylan 4-O-methyltransferase 
                EC 2.1.1.113                      site-specific DNA-methyltransferase (cytosine-N4-specific) 
                EC 2.1.1.114                      polyprenyldihydroxybenzoate methyltransferase 
                EC 2.1.1.115                      (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase 
                EC 2.1.1.116                      3′-hydroxy-N-methyl-(S)-coclaurine 4′-O-methyltransferase 
                EC 2.1.1.117                      (S)-scoulerine 9-O-methyltransferase 
                EC 2.1.1.118                      columbamine O-methyltransferase 
                EC 2.1.1.119                      10-hydroxydihydrosanguinarine 10-O-methyltransferase 
                EC 2.1.1.120                      12-hydroxydihydrochelirubine 12-O-methyltransferase 
                EC 2.1.1.121                      6-O-methylnorlaudanosoline 5′-O-methyltransferase 
                EC 2.1.1.122                      (S)-tetrahydroprotoberberine N-methyltransferase 
                EC 2.1.1.123                      [cytochrome-c]-methionine S-methyltransferase 
                EC 2.1.1.124                      [cytochrome c]-arginine N-methyltransferase. Now covered by EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.320, type II protein arginine methyltransferase, EC 2.1.1.321, type III protein arginine methyltransferase and EC 2.1.1.322, type IV protein arginine methyltransferase 
                EC 2.1.1.125                      histone-arginine N-methyltransferase. Now covered by EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.320, type II protein arginine methyltransferase, EC 2.1.1.321, type III protein arginine methyltransferase and EC 2.1.1.322, type IV protein arginine methyltransferase 
                EC 2.1.1.126                      [myelin basic protein]-arginine N-methyltransferase. Now covered by EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.320, type II protein arginine methyltransferase, EC 2.1.1.321, type III protein arginine methyltransferase and EC 2.1.1.322, type IV protein arginine methyltransferase 
                EC 2.1.1.127                      [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase 
                EC 2.1.1.128                      (RS)-norcoclaurine 6-O-methyltransferase 
                EC 2.1.1.129                      inositol 4-methyltransferase 
                EC 2.1.1.130                      precorrin-2 C20-methyltransferase 
                EC 2.1.1.131                      precorrin-3B C17-methyltransferase 
                EC 2.1.1.132                      precorrin-6B C5,15-methyltransferase (decarboxylating) 
                EC 2.1.1.133                      precorrin-4 C11-methyltransferase 
                EC 2.1.1.134                       myo-inositol 6-O-methyltransferase. Now included with EC 2.1.1.129, inositol 4-methyltransferase 
                EC 2.1.1.135                      [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing). Now EC 1.16.1.8, [methionine synthase] reductase 
                EC 2.1.1.136                      chlorophenol O-methyltransferase 
                EC 2.1.1.137                      arsenite methyltransferase 
                EC 2.1.1.138                       methylarsonite methyltransferase. Reaction due to EC 2.1.1.137, arsonite methyltransferase 
                EC 2.1.1.139                      3′-demethylstaurosporine O-methyltransferase 
                EC 2.1.1.140                      (S)-coclaurine-N-methyltransferase 
                EC 2.1.1.141                      jasmonate O-methyltransferase 
                EC 2.1.1.142                      cycloartenol 24-C-methyltransferase 
                EC 2.1.1.143                      24-methylenesterol C-methyltransferase 
                EC 2.1.1.144                      trans-aconitate 2-methyltransferase 
                EC 2.1.1.145                      trans-aconitate 3-methyltransferase 
                EC 2.1.1.146                      (iso)eugenol O-methyltransferase 
                EC 2.1.1.147                      corydaline synthase 
                EC 2.1.1.148                      thymidylate synthase (FAD) 
                EC 2.1.1.149                      myricetin O-methyltransferase. Now covered by EC 2.1.1.267, flavonoid 3′,5′-methyltransferase. 
                EC 2.1.1.150                      isoflavone 7-O-methyltransferase 
                EC 2.1.1.151                      cobalt-factor II C20-methyltransferase 
                EC 2.1.1.152                      precorrin-6A synthase (deacetylating) 
                EC 2.1.1.153                      vitexin 2′′-O-rhamnoside 7-O-methyltransferase 
                EC 2.1.1.154                      isoliquiritigenin 2′-O-methyltransferase 
                EC 2.1.1.155                      kaempferol 4′-O-methyltransferase 
                EC 2.1.1.156                      glycine/sarcosine N-methyltransferase 
                EC 2.1.1.157                      sarcosine/dimethylglycine N-methyltransferase 
                EC 2.1.1.158                      7-methylxanthosine synthase 
                EC 2.1.1.159                      theobromine synthase 
                EC 2.1.1.160                      caffeine synthase 
                EC 2.1.1.161                      dimethylglycine N-methyltransferase 
                EC 2.1.1.162                      glycine/sarcosine/dimethylglycine N-methyltransferase 
                EC 2.1.1.163                      demethylmenaquinone methyltransferase 
                EC 2.1.1.164                      demethylrebeccamycin-D-glucose O-methyltransferase 
                EC 2.1.1.165                      methyl halide transferase 
                EC 2.1.1.166                      23S rRNA (uridine2552-2′-O)-methyltransferase 
                EC 2.1.1.167                      27S pre-rRNA (guanosine2922-2′-O)-methyltransferase 
                EC 2.1.1.168                      21S rRNA (uridine2791-2′-O)-methyltransferase 
                EC 2.1.1.169                      tricetin 3′,4′,5′-O-trimethyltransferase 
                EC 2.1.1.170                      16S rRNA (guanine527-N7)-methyltransferase 
                EC 2.1.1.171                      16S rRNA (guanine966-N2)-methyltransferase 
                EC 2.1.1.172                      16S rRNA (guanine1207-N2)-methyltransferase 
                EC 2.1.1.173                      23S rRNA (guanine2445-N2)-methyltransferase 
                EC 2.1.1.174                      23S rRNA (guanine1835-N2)-methyltransferase 
                EC 2.1.1.175                      tricin synthase 
                EC 2.1.1.176                      16S rRNA (cytosine967-C5)-methyltransferase 
                EC 2.1.1.177                      23S rRNA (pseudouridine1915-N3)-methyltransferase 
                EC 2.1.1.178                      16S rRNA (cytosine1407-C5)-methyltransferase 
                EC 2.1.1.179                      16S rRNA (guanine1405-N7)-methyltransferase 
                EC 2.1.1.180                      16S rRNA (adenine1408-N1)-methyltransferase 
                EC 2.1.1.181                      23S rRNA (adenine1618-N6)-methyltransferase 
                EC 2.1.1.182                      16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase 
                EC 2.1.1.183                      18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase 
                EC 2.1.1.184                      23S rRNA (adenine2085-N6)-dimethyltransferase 
                EC 2.1.1.185                      23S rRNA (guanosine2251-2′-O)-methyltransferase 
                EC 2.1.1.186                      23S rRNA (cytidine2498-2′-O)-methyltransferase 
                EC 2.1.1.187                      23S rRNA (guanine745-N1)-methyltransferase 
                EC 2.1.1.188                      23S rRNA (guanine748-N1)-methyltransferase 
                EC 2.1.1.189                      23S rRNA (uracil747-C5)-methyltransferase 
                EC 2.1.1.190                      23S rRNA (uracil1939-C5)-methyltransferase 
                EC 2.1.1.191                      23S rRNA (cytosine1962-C5)-methyltransferase 
                EC 2.1.1.192                      23S rRNA (adenine2503-C2)-methyltransferase 
                EC 2.1.1.193                      16S rRNA (uracil1498-N3)-methyltransferase 
                EC 2.1.1.194                      23S rRNA (adenine2503-C2,C8)-dimethyltransferase. A mixture of EC 2.1.1.192 (23S rRNA (adenine2503-C2)-methyltransferase) and EC 2.1.1.224 (23S rRNA (adenine2503-C8)-methyltransferase) 
                EC 2.1.1.195                      cobalt-precorrin-5B (C1)-methyltransferase 
                EC 2.1.1.196                      cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating] 
                EC 2.1.1.197                      malonyl-[acyl-carrier protein] O-methyltransferase 
                EC 2.1.1.198                      16S rRNA (cytidine1402-2′-O)-methyltransferase 
                EC 2.1.1.199                      16S rRNA (cytosine1402-N4)-methyltransferase 
                EC 2.1.1.200                      tRNA (cytidine32/uridine32-2′-O)-methyltransferase 
                EC 2.1.1.201                      2-methoxy-6-polyprenyl-1,4-benzoquinol methylase 
                EC 2.1.1.202                      multisite-specific tRNA:(cytosine-C5)-methyltransferase 
                EC 2.1.1.203                      tRNA (cytosine34-C5)-methyltransferase 
                EC 2.1.1.204                      tRNA (cytosine38-C5)-methyltransferase 
                EC 2.1.1.205                      tRNA (cytidine32/guanosine34-2′-O)-methyltransferase 
                EC 2.1.1.206                      tRNA (cytidine56-2′-O)-methyltransferase 
                EC 2.1.1.207                      tRNA (cytidine34-2′-O)-methyltransferase 
                EC 2.1.1.208                      23S rRNA (uridine2479-2′-O)-methyltransferase 
                EC 2.1.1.209                      23S rRNA (guanine2535-N1)-methyltransferase 
                EC 2.1.1.210                      demethylspheroidene O-methyltransferase 
                EC 2.1.1.211                      tRNASer (uridine44-2′-O)-methyltransferase 
                EC 2.1.1.212                      2,7,4′-trihydroxyisoflavanone 4′-O-methyltransferase 
                EC 2.1.1.213                      tRNA (guanine10-N2)-dimethyltransferase 
                EC 2.1.1.214                      tRNA (guanine10-N2)-methyltransferase 
                EC 2.1.1.215                      tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase 
                EC 2.1.1.216                      tRNA (guanine26-N2)-dimethyltransferase 
                EC 2.1.1.217                      tRNA (adenine22-N1)-methyltransferase 
                EC 2.1.1.218                      tRNA (adenine9-N1)-methyltransferase 
                EC 2.1.1.219                      tRNA (adenine57-N1/adenine58-N1)-methyltransferase 
                EC 2.1.1.220                      tRNA (adenine58-N1)-methyltransferase 
                EC 2.1.1.221                      tRNA (guanine9-N1)-methyltransferase 
                EC 2.1.1.222                      2-polyprenyl-6-hydroxyphenol methylase 
                EC 2.1.1.223                      tRNA1Val (adenine37-N6)-methyltransferase 
                EC 2.1.1.224                      23S rRNA (adenine2503-C8)-methyltransferase 
                EC 2.1.1.225                      tRNA:m4X modification enzyme 
                EC 2.1.1.226                      23S rRNA (cytidine1920-2′-O)-methyltransferase 
                EC 2.1.1.227                      16S rRNA (cytidine1409-2′-O)-methyltransferase 
                EC 2.1.1.228                      tRNA (guanine37-N1)-methyltransferase 
                EC 2.1.1.229                      tRNA (carboxymethyluridine34-5-O)-methyltransferase 
                EC 2.1.1.230                      23S rRNA (adenosine1067-2′-O)-methyltransferase 
                EC 2.1.1.231                      flavonoid 4′-O-methyltransferase 
                EC 2.1.1.232                      naringenin 7-O-methyltransferase 
                EC 2.1.1.233                      [phosphatase 2A protein]-leucine-carboxy methyltransferase 
                EC 2.1.1.234                      dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose N,N-dimethyltransferase 
                EC 2.1.1.235                      dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose N,N-dimethyltransferase 
                EC 2.1.1.236                      dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose N,N-dimethyltransferase 
                EC 2.1.1.237                      mycinamicin III 3′′-O-methyltransferase 
                EC 2.1.1.238                      mycinamicin VI 2′′-O-methyltransferase 
                EC 2.1.1.239                      L-olivosyl-oleandolide 3-O-methyltransferase 
                EC 2.1.1.240                      trans-resveratrol di-O-methyltransferase 
                EC 2.1.1.241                      2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase 
                EC 2.1.1.242                      16S rRNA (guanine1516-N2)-methyltransferase 
                EC 2.1.1.243                      5-guanidino-2-oxopentanoate (3R)-methyltransferase 
                EC 2.1.1.244                      protein N-terminal methyltransferase 
                EC 2.1.1.245                      5-methyltetrahydrosarcinapterin—corrinoid/iron-sulfur protein Co-methyltransferase 
                EC 2.1.1.246                      [methyl-Co(III) methanol-specific corrinoid protein]—coenzyme M methyltransferase 
                EC 2.1.1.247                      [methyl-Co(III) methylamine-specific corrinoid protein]—coenzyme M methyltransferase 
                EC 2.1.1.248                      methylamine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.249                      dimethylamine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.250                      trimethylamine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.251                      methylated-thiol—coenzyme M methyltransferase 
                EC 2.1.1.252                      tetramethylammonium—corrinoid protein Co-methyltransferase 
                EC 2.1.1.253                      [methyl-Co(III) tetramethylammonium-specific corrinoid protein]—coenzyme M methyltransferase 
                EC 2.1.1.254                      erythromycin 3′′-O-methyltransferase 
                EC 2.1.1.255                      geranyl diphosphate 2-C-methyltransferase 
                EC 2.1.1.256                      tRNA (guanine6-N2)-methyltransferase 
                EC 2.1.1.257                      tRNA (pseudouridine54-N1)-methyltransferase 
                EC 2.1.1.258                      5-methyltetrahydrofolate—corrinoid/iron-sulfur protein Co-methyltransferase 
                EC 2.1.1.259                      [fructose-bisphosphate aldolase]-lysine N-methyltransferase 
                EC 2.1.1.260                      rRNA small subunit pseudouridine methyltransferase Nep1 
                EC 2.1.1.261                      4-dimethylallyltryptophan N-methyltransferase 
                EC 2.1.1.262                      squalene methyltransferase 
                EC 2.1.1.263                      botryococcene C-methyltransferase 
                EC 2.1.1.264                      23S rRNA (guanine2069-N7)-methyltransferase 
                EC 2.1.1.265                      tellurite methyltransferase 
                EC 2.1.1.266                      23S rRNA (adenine2030-N6)-methyltransferase 
                EC 2.1.1.267                      flavonoid 3′,5′-methyltransferase 
                EC 2.1.1.268                      tRNAThr (cytosine32-N3)-methyltransferase  
                EC 2.1.1.269                      dimethylsulfoniopropionate demethylase 
                EC 2.1.1.270                      (+)-6a-hydroxymaackiain 3-O-methyltransferase 
                EC 2.1.1.271                      cobalt-precorrin-4 methyltransferase 
                EC 2.1.1.272                      cobalt-factor III methyltransferase 
                EC 2.1.1.273                      benzoate O-methyltransferase 
                EC 2.1.1.274                      salicylate 1-O-methyltransferase 
                EC 2.1.1.275                      gibberellin A9 O-methyltransferase 
                EC 2.1.1.276                      gibberellin A4 carboxyl methyltransferase 
                EC 2.1.1.277                      anthranilate O-methyltransferase 
                EC 2.1.1.278                      indole-3-acetate O-methyltransferase 
                EC 2.1.1.279                      trans-anol O-methyltransferase 
                EC 2.1.1.280                      selenocysteine Se-methyltransferase 
                EC 2.1.1.281                      phenylpyruvate C3-methyltransferase 
                EC 2.1.1.282                      tRNAPhe 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine37-N4]-methyltransferase 
                EC 2.1.1.283                      emodin O-methyltransferase 
                EC 2.1.1.284                      8-demethylnovobiocic acid C8-methyltransferase 
                EC 2.1.1.285                      demethyldecarbamoylnovobiocin O-methyltransferase 
                EC 2.1.1.286                      25S rRNA (adenine2142-N1)-methyltransferase 
                EC 2.1.1.287                      25S rRNA (adenine645-N1)-methyltransferase 
                EC 2.1.1.288                      aklanonic acid methyltransferase 
                EC 2.1.1.289                      cobalt-precorrin-7 (C5)-methyltransferase 
                EC 2.1.1.290                      tRNAPhe [7-(3-amino-3-carboxypropyl)wyosine37-O]-methyltransferase 
                EC 2.1.1.291                      (R,S)-reticuline 7-O-methyltransferase 
                EC 2.1.1.292                      carminomycin 4-O-methyltransferase 
                EC 2.1.1.293                      6-hydroxytryprostatin B O-methyltransferase 
                EC 2.1.1.294                      3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-phospho-methyltransferase 
                EC 2.1.1.295                      2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 
                EC 2.1.1.296                      methyltransferase cap2 
                EC 2.1.1.297                      peptide chain release factor N5-glutamine methyltransferase 
                EC 2.1.1.298                      ribosomal protein uL3 N5-glutamine methyltransferase 
                EC 2.1.1.299                      protein N-terminal monomethyltransferase 
                EC 2.1.1.300                      pavine N-methyltransferase 
                EC 2.1.1.301                      cypemycin N-terminal methyltransferase  
                EC 2.1.1.302                      3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase 
                EC 2.1.1.303                      2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase 
                EC 2.1.1.304                      L-tyrosine C3-methyltransferase 
                EC 2.1.1.305                      8-demethyl-8-α-L-rhamnosyltetracenomycin-C 2′-O-methyltransferase 
                EC 2.1.1.306                      8-demethyl-8-(2-methoxy-α-L-rhamnosyl)tetracenomycin-C 3′-O-methyltransferase 
                EC 2.1.1.307                      8-demethyl-8-(2,3-dimethoxy-α-L-rhamnosyl)tetracenomycin-C 4′-O-methyltransferase 
                EC 2.1.1.308                      cytidylyl-2-hydroxyethylphosphonate methyltransferase 
                EC 2.1.1.309                      18S rRNA (guanine1575-N7)-methyltransferase 
                EC 2.1.1.310                      25S rRNA (cytosine2870-C5)-methyltransferase 
                EC 2.1.1.311                      25S rRNA (cytosine2278-C5)-methyltransferase 
                EC 2.1.1.312                      25S rRNA (uracil2843-N3)-methyltransferase 
                EC 2.1.1.313                      25S rRNA (uracil2634-N3)-methyltransferase 
                EC 2.1.1.314                      diphthine methyl ester synthase 
                EC 2.1.1.315                      27-O-demethylrifamycin SV methyltransferase 
                EC 2.1.1.316                      mitomycin 6-O-methyltransferase 
                EC 2.1.1.317                      sphingolipid C9-methyltransferase 
                EC 2.1.1.318                      [trehalose-6-phosphate synthase]-L-cysteine S-methyltransferase 
                EC 2.1.1.319                      type I protein arginine methyltransferase 
                EC 2.1.1.320                      type II protein arginine methyltransferase 
                EC 2.1.1.321                      type III protein arginine methyltransferase 
                EC 2.1.1.322                      type IV protein arginine methyltransferase 
                EC 2.1.1.323                      (–)-pluviatolide 4-O-methyltransferase 
                EC 2.1.1.324                      dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase 
                EC 2.1.1.325                      juvenile hormone-III synthase 
                EC 2.1.1.326                      N-acetyldemethylphosphinothricin P-methyltransferase 
                EC 2.1.1.327                      phenazine-1-carboxylate N-methyltransferase 
                EC 2.1.1.328                      N-demethylindolmycin N-methyltransferase 
                EC 2.1.1.329                      demethylphylloquinol methyltransferase 
                EC 2.1.1.330                      5′-demethylyatein 5′-O-methyltransferase 
                EC 2.1.1.331                      bacteriochlorophyllide d C-121-methyltransferase 
                EC 2.1.1.332                      bacteriochlorophyllide d C-82-methyltransferase 
                EC 2.1.1.333                      bacteriochlorophyllide d C-20 methyltransferase 
                EC 2.1.1.334                      methanethiol S-methyltransferase 
                EC 2.1.1.335                      4-amino-anhydrotetracycline N4-methyltransferase 
                EC 2.1.1.336                      norbelladine O-methyltransferase 
                EC 2.1.1.337                      reticuline N-methyltransferase 
                EC 2.1.1.338                      desmethylxanthohumol 6′-O-methyltransferase 
                EC 2.1.1.339                      xanthohumol 4-O-methyltransferase 
                EC 2.1.1.340                      3-aminomethylindole N-methyltransferase 
                EC 2.1.1.341                      vanillate/3-O-methylgallate O-demethylase 
                EC 2.1.1.342                      anaerobilin synthase 
                EC 2.1.1.343                      8-amino-8-demethylriboflavin N,N-dimethyltransferase 
                EC 2.1.1.344                      ornithine lipid N-methyltransferase 
                EC 2.1.1.345                      psilocybin synthase 
                EC 2.1.1.346                      U6 snRNA m6A methyltransferase 
                EC 2.1.1.347                      (+)-O-methylkolavelool synthase 
                EC 2.1.1.348                      mRNA m6A methyltransferase 
                EC 2.1.1.349                      toxoflavin synthase 
                EC 2.1.1.350                      menaquinone C8-methyltransferase 
                EC 2.1.1.351                      nocamycin O-methyltransferase 
                EC 2.1.1.352                      3-O-acetyl-4′-O-demethylpapaveroxine 4′-O-methyltransferase 
                EC 2.1.1.353                      demethylluteothin O-methyltransferase 
                EC 2.1.1.354                      [histone H3]-lysine4 N-trimethyltransferase 
                EC 2.1.1.355                      [histone H3]-lysine9 N-trimethyltransferase 
                EC 2.1.1.356                      [histone H3]-lysine27 N-trimethyltransferase 
                EC 2.1.1.357                      [histone H3]-lysine36 N-dimethyltransferase 
                EC 2.1.1.358                      [histone H3]-dimethyl-L-lysine36 N-methyltransferase. Now known to have the activity of 2.1.1.359, [histone H3]-lysine36 N-trimethyltransferase. 
                EC 2.1.1.359                      [histone H3]-lysine36 N-trimethyltransferase 
                EC 2.1.1.360                      [histone H3]-lysine79 N-trimethyltransferase 
                EC 2.1.1.361                      [histone H4]-lysine20 N-methyltransferase 
                EC 2.1.1.362                      [histone H4]-N-methyl-L-lysine20 N-methyltransferase 
                EC 2.1.1.363                      pre-sodorifen synthase 
                EC 2.1.1.364                      [histone H3]-lysine4 N-methyltransferase 
                EC 2.1.1.365                      MMP 1-O-methyltransferase 
                EC 2.1.1.366                      [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase 
                EC 2.1.1.367                      [histone H3]-lysine9 N-methyltransferase 
                EC 2.1.1.368                      [histone H3]-lysine9 N-dimethyltransferase 
                EC 2.1.1.369                      [histone H3]-lysine27 N-methyltransferase 
                EC 2.1.1.370                      [histone H3]-lysine4 N-dimethyltransferase 
                EC 2.1.1.371                      [histone H3]-lysine27 N-dimethyltransferase 
                EC 2.1.1.372                      [histone H4]-lysine20 N-trimethyltransferase 
                EC 2.1.1.373                      2-hydroxy-4-(methylsulfanyl)butanoate S-methyltransferase 
                EC 2.1.1.374                      2-heptyl-1-hydroxyquinolin-4(1H)-one methyltransferase 
                EC 2.1.1.375                      NNS virus cap methyltransferase 
                EC 2.1.1.376                      glycine betaine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.377                      [methyl-Co(III) glycine betaine-specific corrinoid protein]—coenzyme M methyltransferase 
                EC 2.1.1.378                      [methyl-Co(III) glycine betaine-specific corrinoid protein]—tetrahydrofolate methyltransferase 
                EC 2.1.1.379                      [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase 
                EC 2.1.1.380                      3-amino-4-hydroxybenzoate 4-O-methyltransferase 
                EC 2.1.1.381                      arginine Nω-methyltransferase 
                EC 2.1.1.382                      methoxylated aromatic compound—corrinoid protein Co-methyltransferase 
                EC 2.1.1.383                      L-carnitine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.384                      [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]—tetrahydromethanopterin methyltransferase 
                EC 2.1.1.385                      [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]—tetrahydrofolate methyltransferase 
                EC 2.1.1.386                      small RNA 2′-O-methyltransferase 
                EC 2.1.1.387                      5-dehydro-6-demethoxy-6-hydroxyfumagillol O-methyltransferase 
                EC 2.1.1.388                      proline betaine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.389                      [methyl-Co(III) quaternary-amine-specific corrinoid protein]—tetrahydrofolate methyltransferase 
                EC 2.1.1.390                      gentamicin X2 methyltransferase 
                EC 2.1.1.391                      demethylgadusol O-methyltransferase 
                EC 2.1.1.392                      norajmaline N-methyltransferase 
                EC 2.1.1.393                      ajmaline N-methyltransferase 
                EC 2.1.1.394                      2-(S-pantetheinyl)-carbapenam-3-carboxylate methyltransferase 
                EC 2.1.1.395                      7′-O-demethylcephaeline methyltransferase 
                EC 2.1.1.396                      cephaeline 6′-O-methyltransferase 
        EC 2.1.2       [+]    Hydroxymethyl-, formyl- and related transferases 
        EC 2.1.3       [+]    Carboxy- and carbamoyltransferases 
        EC 2.1.4       [+]    Amidinotransferases 
        EC 2.1.5       [+]    Methylenetransferases 
    EC 2.2  [+]      
    EC 2.3  [+]      
    EC 2.4  [+]      
    EC 2.5  [+]      
    EC 2.6  [+]      
    EC 2.7  [+]      
    EC 2.8  [+]      
    EC 2.9  [+]      
    EC 2.10  [+]      
EC 3 [+]   
EC 4 [+]   
EC 5 [+]   
EC 6 [+]   
EC 7 [+]   


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