The Enzyme Database

Table of Contents

The enzymes in this section of the database are organized as you would find them in the Enzyme-Nomenclature book. Click [+] to expand, and [–] to collapse, any section. Clicking on a heading will open a popup window with information on that class, subclass or sub-subclass.

For a fully expanded list of the classes, subclasses and sub-subclasses, click here

[+subclass]. [+sub-subclass]. [+serial]

EC 1 [+]   
EC 2 [+]   
EC 3 []   
    EC 3.1  []      
        EC 3.1.1       [+]    Carboxylic-ester hydrolases 
        EC 3.1.2       [+]    Thioester hydrolases 
        EC 3.1.3       [+]    Phosphoric-monoester hydrolases 
        EC 3.1.4       []    Phosphoric-diester hydrolases 
                EC 3.1.4.1                      phosphodiesterase I 
                EC 3.1.4.2                      glycerophosphocholine phosphodiesterase 
                EC 3.1.4.3                      phospholipase C 
                EC 3.1.4.4                      phospholipase D 
                EC 3.1.4.5                      deoxyribonuclease. Now EC 3.1.21.1, deoxyribonuclease I 
                EC 3.1.4.6                      deoxyribonuclease II. Now EC 3.1.22.1, deoxyribonuclease II 
                EC 3.1.4.7                      micrococcal nuclease. Now EC 3.1.31.1, micrococcal nuclease 
                EC 3.1.4.8                      Aspergillus oryzae ribonuclease. Now EC 3.1.27.3, ribonuclease T1 
                EC 3.1.4.9                      nucleate endonuclease. Now EC 3.1.30.2, Serratia marcescens nuclease 
                EC 3.1.4.10                      1-phosphatidylinositol phosphodiesterase. Now EC 4.6.1.13, phosphatidylinositol diacylglycerol-lyase. As there is no hydrolysis of the inositol 1,2-cyclic phosphate formed, previous classification of the enzyme as a hydrolase was incorrect 
                EC 3.1.4.11                      phosphoinositide phospholipase C 
                EC 3.1.4.12                      sphingomyelin phosphodiesterase 
                EC 3.1.4.13                      serine-ethanolaminephosphate phosphodiesterase 
                EC 3.1.4.14                      [acyl-carrier-protein] phosphodiesterase 
                EC 3.1.4.15                      adenylyl-[glutamateammonia ligase] hydrolase. As it has been shown that the enzyme catalyses a transfer of the adenylyl group to phosphate, the enzyme has been transferred to EC 2.7.7.89, adenylyl-[glutamateammonia ligase] phosphorylase 
                EC 3.1.4.16                      2′,3′-cyclic-nucleotide 2′-phosphodiesterase 
                EC 3.1.4.17                      3′,5′-cyclic-nucleotide phosphodiesterase 
                EC 3.1.4.18                      phosphodiesterase II. Now EC 3.1.16.1, spleen exonuclease 
                EC 3.1.4.19                      oligonucleotidase. Now EC 3.1.13.3, oligonucleotidase 
                EC 3.1.4.20                      exoribonuclease. Now EC 3.1.13.1, exoribonuclease II 
                EC 3.1.4.21                      single-stranded-nucleate endonuclease. Now EC 3.1.30.1, Aspergillus nuclease S1 
                EC 3.1.4.22                      ribonuclease I. Now EC 3.1.27.5, pancreatic ribonuclease 
                EC 3.1.4.23                      ribonuclease II. Now EC 3.1.27.1, ribonuclease T2 
                EC 3.1.4.24                       endoribonuclease III 
                EC 3.1.4.25                      exodeoxyribonuclease I. Now EC 3.1.11.1, exodeoxyribonuclease I 
                EC 3.1.4.26                       exodeoxyribonuclease II 
                EC 3.1.4.27                      exodeoxyribonuclease III. Now EC 3.1.11.2, exodeoxyribonuclease III 
                EC 3.1.4.28                      exodeoxyribonuclease IV. Now EC 3.1.11.3, exodeoxyribonuclease (lambda-induced) 
                EC 3.1.4.29                       oligodeoxyribonucleate exonuclease 
                EC 3.1.4.30                      endodeoxyribonuclease. Now EC 3.1.21.2, deoxyribonuclease IV (phage-T4-induced) 
                EC 3.1.4.31                      DNA 5′-dinucleotidohydrolase. Now EC 3.1.11.4, exodeoxyribonuclease (phage SP3-induced) 
                EC 3.1.4.32                       endodeoxyribonuclease (ATP- and S-adenosylmethionine-dependent). See EC 3.1.21.3 type 1 site-specific deoxyribonuclease and EC 3.1.21.5 type III site-specific deoxyribonuclease 
                EC 3.1.4.33                       endodeoxyribonuclease (ATP-hydrolysing). See EC 3.1.21.3 type 1 site-specific deoxyribonuclease and EC 3.1.21.5 type III site-specific deoxyribonuclease 
                EC 3.1.4.34                       hybrid nuclease. See sub-subclasses EC 3.1.15, EC 3.1.16, EC 3.1.30 and EC 3.1.31. 
                EC 3.1.4.35                      3′,5′-cyclic-GMP phosphodiesterase 
                EC 3.1.4.36                       1,2-cyclic-inositol-phosphate phosphodiesterase. Now included with EC 3.1.4.43, glycerophosphoinositol inositolphosphodiesterase 
                EC 3.1.4.37                      2′,3′-cyclic-nucleotide 3′-phosphodiesterase 
                EC 3.1.4.38                      glycerophosphocholine cholinephosphodiesterase 
                EC 3.1.4.39                      alkylglycerophosphoethanolamine phosphodiesterase 
                EC 3.1.4.40                      CMP-N-acylneuraminate phosphodiesterase 
                EC 3.1.4.41                      sphingomyelin phosphodiesterase D 
                EC 3.1.4.42                      glycerol-1,2-cyclic-phosphate 2-phosphodiesterase 
                EC 3.1.4.43                      glycerophosphoinositol inositolphosphodiesterase 
                EC 3.1.4.44                      glycerophosphoinositol glycerophosphodiesterase 
                EC 3.1.4.45                      N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase 
                EC 3.1.4.46                      glycerophosphodiester phosphodiesterase 
                EC 3.1.4.47                      variant-surface-glycoprotein phospholipase C. Now EC 4.6.1.14, glycosylphosphatidylinositol diacylglycerol-lyase 
                EC 3.1.4.48                      dolichylphosphate-glucose phosphodiesterase 
                EC 3.1.4.49                      dolichylphosphate-mannose phosphodiesterase 
                EC 3.1.4.50                      glycosylphosphatidylinositol phospholipase D 
                EC 3.1.4.51                      glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase 
                EC 3.1.4.52                      cyclic-guanylate-specific phosphodiesterase 
                EC 3.1.4.53                      3′,5′-cyclic-AMP phosphodiesterase 
                EC 3.1.4.54                      N-acetylphosphatidylethanolamine-hydrolysing phospholipase D 
                EC 3.1.4.55                      phosphoribosyl 1,2-cyclic phosphate phosphodiesterase 
                EC 3.1.4.56                      7,8-dihydroneopterin 2′,3′-cyclic phosphate phosphodiesterase 
                EC 3.1.4.57                      phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase 
                EC 3.1.4.58                      RNA 2′,3′-cyclic 3′-phosphodiesterase 
                EC 3.1.4.59                      cyclic-di-AMP phosphodiesterase 
                EC 3.1.4.60                      pApA phosphodiesterase 
                EC 3.1.4.61                      cyclic 2,3-diphosphoglycerate hydrolase 
                EC 3.1.4.62                      phosphatidylethanolamine phospholipase C 
        EC 3.1.5       [+]    Triphosphoric-monoester hydrolases 
        EC 3.1.6       [+]    Sulfuric-ester hydrolases 
        EC 3.1.7       [+]    Diphosphoric-monoester hydrolases 
        EC 3.1.8       [+]    Phosphoric-triester hydrolases 
        EC 3.1.11       [+]    Exodeoxyribonucleases producing 5′-phosphomonoesters 
        EC 3.1.12       [+]    Exodeoxyribonucleases producing 3′-phosphomonoesters 
        EC 3.1.13       [+]    Exoribonucleases producing 5′-phosphomonoesters 
        EC 3.1.14       [+]    Exoribonucleases producing 3'-phosphomonoesters 
        EC 3.1.15       [+]    Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters 
        EC 3.1.16       [+]    Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters 
        EC 3.1.21       [+]    Endodeoxyribonucleases producing 5'-phosphomonoesters 
        EC 3.1.22       [+]    Endodeoxyribonucleases producing 3'-phosphomonoesters 
        EC 3.1.23       [+]    Site-specific endodeoxyribonucleases: cleavage is sequence specific (deleted sub-subclass) 
        EC 3.1.24       [+]    Site specific endodeoxyribonucleases: cleavage is not sequence specific (deleted sub-subclass) 
        EC 3.1.25       [+]    Site-specific endodeoxyribonucleases that are specific for altered bases 
        EC 3.1.26       [+]    Endoribonucleases producing 5'-phosphomonoesters 
        EC 3.1.27       [+]    Endoribonucleases producing 3'-phosphomonoesters 
        EC 3.1.30       [+]    Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters 
        EC 3.1.31       [+]    Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters 
    EC 3.2  [+]      
    EC 3.3  [+]      
    EC 3.4  [+]      
    EC 3.5  [+]      
    EC 3.6  [+]      
    EC 3.7  [+]      
    EC 3.8  [+]      
    EC 3.9  [+]      
    EC 3.10  [+]      
    EC 3.11  [+]      
    EC 3.12  [+]      
    EC 3.13  [+]      
EC 4 [+]   
EC 5 [+]   
EC 6 [+]   
EC 7 [+]   


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