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| The enzymes in this section of the database are organized as you would find them in the
Enzyme-Nomenclature book. Click [+] to expand, and [–] to collapse, any section. Clicking on a heading will open a popup window with information on that class, subclass or sub-subclass. For a fully expanded list of the classes, subclasses and sub-subclasses, click here |
| EC 1 | [+] | ||
| EC 2 | [+] | ||
| EC 3 | [+] | ||
| EC 4 | [–] | ||
| EC 4.1 | [+] | ||
| EC 4.2 | [–] | ||
| EC 4.2.1 | [–] Hydro-lyases | ||
| EC 4.2.1.1 | carbonic anhydrase | ||
| EC 4.2.1.2 | fumarate hydratase | ||
| EC 4.2.1.3 | aconitate hydratase | ||
| EC 4.2.1.4 | citrate dehydratase. Now known to be a partial reaction catalysed by EC 4.2.1.3, aconitate hydratase. | ||
| EC 4.2.1.5 | arabinonate dehydratase | ||
| EC 4.2.1.6 | galactonate dehydratase | ||
| EC 4.2.1.7 | altronate dehydratase | ||
| EC 4.2.1.8 | mannonate dehydratase | ||
| EC 4.2.1.9 | dihydroxy-acid dehydratase | ||
| EC 4.2.1.10 | 3-dehydroquinate dehydratase | ||
| EC 4.2.1.11 | phosphopyruvate hydratase | ||
| EC 4.2.1.12 | phosphogluconate dehydratase | ||
| EC 4.2.1.13 | L-serine dehydratase. Now EC 4.3.1.17, L-serine ammonia-lyase | ||
| EC 4.2.1.14 | D-serine dehydratase. Now EC 4.3.1.18, D-serine ammonia-lyase | ||
| EC 4.2.1.15 | homoserine dehydratase. Identical with EC 4.4.1.1 cystathionine γ-lyase | ||
| EC 4.2.1.16 | threonine dehydratase. Now EC 4.3.1.19, threonine ammonia-lyase | ||
| EC 4.2.1.17 | enoyl-CoA hydratase | ||
| EC 4.2.1.18 | methylglutaconyl-CoA hydratase | ||
| EC 4.2.1.19 | imidazoleglycerol-phosphate dehydratase | ||
| EC 4.2.1.20 | tryptophan synthase | ||
| EC 4.2.1.21 | cystathionine β-synthase. Now EC 4.2.1.22 cystathionine β-synthase | ||
| EC 4.2.1.22 | cystathionine β-synthase | ||
| EC 4.2.1.23 | methylcysteine synthase. The reaction was due to a side-reaction of EC 4.2.1.22 cystathionine β-synthase | ||
| EC 4.2.1.24 | porphobilinogen synthase | ||
| EC 4.2.1.25 | L-arabinonate dehydratase | ||
| EC 4.2.1.26 | aminodeoxygluconate dehydratase. This enzyme was transferred to EC 4.3.1.21, aminodeoxygluconate ammonia-lyase, which has since been deleted. The enzyme is identical to EC 4.3.1.9, glucosaminate ammonia-lyase | ||
| EC 4.2.1.27 | acetylenecarboxylate hydratase | ||
| EC 4.2.1.28 | propanediol dehydratase | ||
| EC 4.2.1.29 | indoleacetaldoxime dehydratase. Now EC 4.99.1.6, indoleacetaldoxime dehydratase. The enzyme was classified incorrectly as a C-O lyase when the bond broken is a N-O bond | ||
| EC 4.2.1.30 | glycerol dehydratase | ||
| EC 4.2.1.31 | maleate hydratase | ||
| EC 4.2.1.32 | L(+)-tartrate dehydratase | ||
| EC 4.2.1.33 | 3-isopropylmalate dehydratase | ||
| EC 4.2.1.34 | (S)-2-methylmalate dehydratase | ||
| EC 4.2.1.35 | (R)-2-methylmalate dehydratase | ||
| EC 4.2.1.36 | homoaconitate hydratase | ||
| EC 4.2.1.37 | trans-epoxysuccinate hydratase. Now EC 3.3.2.4, trans-epoxysuccinate hydrolase | ||
| EC 4.2.1.38 | erythro-3-hydroxyaspartate dehydratase. Now EC 4.3.1.20, erythro-3-hydroxyaspartate ammonia-lyase | ||
| EC 4.2.1.39 | gluconate dehydratase | ||
| EC 4.2.1.40 | glucarate dehydratase | ||
| EC 4.2.1.41 | 5-dehydro-4-deoxyglucarate dehydratase | ||
| EC 4.2.1.42 | galactarate dehydratase | ||
| EC 4.2.1.43 | 2-dehydro-3-deoxy-L-arabinonate dehydratase | ||
| EC 4.2.1.44 | myo-inosose-2 dehydratase | ||
| EC 4.2.1.45 | CDP-glucose 4,6-dehydratase | ||
| EC 4.2.1.46 | dTDP-glucose 4,6-dehydratase | ||
| EC 4.2.1.47 | GDP-mannose 4,6-dehydratase | ||
| EC 4.2.1.48 | D-glutamate cyclase | ||
| EC 4.2.1.49 | urocanate hydratase | ||
| EC 4.2.1.50 | pyrazolylalanine synthase | ||
| EC 4.2.1.51 | prephenate dehydratase | ||
| EC 4.2.1.52 | dihydrodipicolinate synthase. Now EC 4.3.3.7, 4-hydroxy-2,3,4,5-tetrahydrodipicolinate synthase. | ||
| EC 4.2.1.53 | oleate hydratase | ||
| EC 4.2.1.54 | lactoyl-CoA dehydratase | ||
| EC 4.2.1.55 | 3-hydroxybutyryl-CoA dehydratase | ||
| EC 4.2.1.56 | itaconyl-CoA hydratase | ||
| EC 4.2.1.57 | isohexenylglutaconyl-CoA hydratase | ||
| EC 4.2.1.58 | crotonoyl-[acyl-carrier-protein] hydratase. The reaction described is covered by EC 4.2.1.59. | ||
| EC 4.2.1.59 | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase | ||
| EC 4.2.1.60 | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase. The reaction described is covered by EC 4.2.1.59. | ||
| EC 4.2.1.61 | 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase. The reaction described is covered by EC 4.2.1.59. | ||
| EC 4.2.1.62 | 5α-hydroxysteroid dehydratase | ||
| EC 4.2.1.63 | epoxide hydratase. Now known to comprise two enzymes, microsomal epoxide hydrolase (EC 3.3.2.9) and soluble epoxide hydrolase (EC 3.3.2.10) | ||
| EC 4.2.1.64 | arene-oxide hydratase. Now known to comprise two enzymes, microsomal epoxide hydrolase (EC 3.3.2.9) and soluble epoxide hydrolase (EC 3.3.2.10) | ||
| EC 4.2.1.65 | 3-cyanoalanine hydratase | ||
| EC 4.2.1.66 | cyanide hydratase | ||
| EC 4.2.1.67 | D-fuconate dehydratase | ||
| EC 4.2.1.68 | L-fuconate dehydratase | ||
| EC 4.2.1.69 | cyanamide hydratase | ||
| EC 4.2.1.70 | pseudouridylate synthase | ||
| EC 4.2.1.71 | acetylenecarboxylate hydratase. This enzyme is identical to EC 4.2.1.27, acetylenecarboxylate hydratase | ||
| EC 4.2.1.72 | acetylenedicarboxylate hydratase. Now EC 4.1.1.78, acetylenedicarboxylate decarboxylase | ||
| EC 4.2.1.73 | protoaphin-aglucone dehydratase (cyclizing) | ||
| EC 4.2.1.74 | medium-chain-enoyl-CoA hydratase | ||
| EC 4.2.1.75 | uroporphyrinogen-III synthase | ||
| EC 4.2.1.76 | UDP-glucose 4,6-dehydratase | ||
| EC 4.2.1.77 | trans-L-3-hydroxyproline dehydratase | ||
| EC 4.2.1.78 | (S)-norcoclaurine synthase. Now 3.5.99.14, (S)-norcoclaurine synthase | ||
| EC 4.2.1.79 | 2-methylcitrate dehydratase | ||
| EC 4.2.1.80 | 2-oxopent-4-enoate hydratase | ||
| EC 4.2.1.81 | D(-)-tartrate dehydratase | ||
| EC 4.2.1.82 | xylonate dehydratase | ||
| EC 4.2.1.83 | 4-oxalomesaconate hydratase | ||
| EC 4.2.1.84 | nitrile hydratase | ||
| EC 4.2.1.85 | dimethylmaleate hydratase | ||
| EC 4.2.1.86 | 16-dehydroprogesterone hydratase (reaction is identical to that of EC 4.2.1.98, 16α-hydroxyprogesterone dehydratase) | ||
| EC 4.2.1.87 | octopamine dehydratase | ||
| EC 4.2.1.88 | synephrine dehydratase | ||
| EC 4.2.1.89 | carnitine dehydratase. The activity has now been shown to be due to EC 2.8.3.21, L-carnitine CoA-transferase and EC 4.2.1.149, crotonobetainyl-CoA hydratase. | ||
| EC 4.2.1.90 | L-rhamnonate dehydratase | ||
| EC 4.2.1.91 | arogenate dehydratase | ||
| EC 4.2.1.92 | hydroperoxide dehydratase | ||
| EC 4.2.1.93 | ATP-dependent NAD(P)H-hydrate dehydratase | ||
| EC 4.2.1.94 | scytalone dehydratase | ||
| EC 4.2.1.95 | kievitone hydratase | ||
| EC 4.2.1.96 | 4a-hydroxytetrahydrobiopterin dehydratase | ||
| EC 4.2.1.97 | phaseollidin hydratase | ||
| EC 4.2.1.98 | 16α-hydroxyprogesterone dehydratase | ||
| EC 4.2.1.99 | 2-methylisocitrate dehydratase | ||
| EC 4.2.1.100 | cyclohexa-1,5-dienecarbonyl-CoA hydratase | ||
| EC 4.2.1.101 | trans-feruloyl-CoA hydratase. Now included with EC 4.1.2.61, feruloyl-CoA hydratase/lyase | ||
| EC 4.2.1.102 | cyclohexa-1,5-dienecarbonyl-CoA hydratase. Now EC 4.2.1.100, cyclohexa-1,5-dienecarbonyl-CoA hydratase | ||
| EC 4.2.1.103 | cyclohexyl-isocyanide hydratase | ||
| EC 4.2.1.104 | cyanase | ||
| EC 4.2.1.105 | 2-hydroxyisoflavanone dehydratase | ||
| EC 4.2.1.106 | bile-acid 7α-dehydratase | ||
| EC 4.2.1.107 | 3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA hydratase | ||
| EC 4.2.1.108 | ectoine synthase | ||
| EC 4.2.1.109 | methylthioribulose 1-phosphate dehydratase | ||
| EC 4.2.1.110 | aldos-2-ulose dehydratase | ||
| EC 4.2.1.111 | 1,5-anhydro-D-fructose dehydratase | ||
| EC 4.2.1.112 | acetylene hydratase | ||
| EC 4.2.1.113 | o-succinylbenzoate synthase | ||
| EC 4.2.1.114 | methanogen homoaconitase | ||
| EC 4.2.1.115 | UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) | ||
| EC 4.2.1.116 | 3-hydroxypropionyl-CoA dehydratase | ||
| EC 4.2.1.117 | 2-methylcitrate dehydratase (2-methyl-trans-aconitate-forming) | ||
| EC 4.2.1.118 | 3-dehydroshikimate dehydratase | ||
| EC 4.2.1.119 | enoyl-CoA hydratase 2 | ||
| EC 4.2.1.120 | 4-hydroxybutanoyl-CoA dehydratase | ||
| EC 4.2.1.121 | colneleate synthase | ||
| EC 4.2.1.122 | tryptophan synthase (indole-salvaging) | ||
| EC 4.2.1.123 | tetrahymanol synthase | ||
| EC 4.2.1.124 | arabidiol synthase | ||
| EC 4.2.1.125 | dammarenediol II synthase | ||
| EC 4.2.1.126 | N-acetylmuramic acid 6-phosphate etherase | ||
| EC 4.2.1.127 | linalool dehydratase | ||
| EC 4.2.1.128 | lupan-3β,20-diol synthase | ||
| EC 4.2.1.129 | squalene—hopanol cyclase | ||
| EC 4.2.1.130 | D-lactate dehydratase | ||
| EC 4.2.1.131 | carotenoid 1,2-hydratase | ||
| EC 4.2.1.132 | 2-hydroxyhexa-2,4-dienoate hydratase | ||
| EC 4.2.1.133 | copal-8-ol diphosphate hydratase | ||
| EC 4.2.1.134 | very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase | ||
| EC 4.2.1.135 | UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) | ||
| EC 4.2.1.136 | ADP-dependent NAD(P)H-hydrate dehydratase | ||
| EC 4.2.1.137 | sporulenol synthase | ||
| EC 4.2.1.138 | (+)-caryolan-1-ol synthase | ||
| EC 4.2.1.139 | pterocarpan synthase | ||
| EC 4.2.1.140 | gluconate/galactonate dehydratase | ||
| EC 4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate dehydratase | ||
| EC 4.2.1.142 | 5′-oxoaverantin cyclase | ||
| EC 4.2.1.143 | versicolorin B synthase | ||
| EC 4.2.1.144 | 3-amino-5-hydroxybenzoate synthase | ||
| EC 4.2.1.145 | capreomycidine synthase | ||
| EC 4.2.1.146 | L-galactonate dehydratase | ||
| EC 4.2.1.147 | 5,6,7,8-tetrahydromethanopterin hydro-lyase | ||
| EC 4.2.1.148 | 2-methylfumaryl-CoA hydratase | ||
| EC 4.2.1.149 | crotonobetainyl-CoA hydratase | ||
| EC 4.2.1.150 | short-chain-enoyl-CoA hydratase | ||
| EC 4.2.1.151 | chorismate dehydratase | ||
| EC 4.2.1.152 | hydroperoxy icosatetraenoate dehydratase | ||
| EC 4.2.1.153 | 3-methylfumaryl-CoA hydratase | ||
| EC 4.2.1.154 | tetracenomycin F2 cyclase | ||
| EC 4.2.1.155 | (methylthio)acryloyl-CoA hydratase | ||
| EC 4.2.1.156 | L-talarate dehydratase | ||
| EC 4.2.1.157 | (R)-2-hydroxyisocaproyl-CoA dehydratase | ||
| EC 4.2.1.158 | galactarate dehydratase (D-threo-forming) | ||
| EC 4.2.1.159 | dTDP-4-dehydro-6-deoxy-α-D-glucopyranose 2,3-dehydratase | ||
| EC 4.2.1.160 | 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase | ||
| EC 4.2.1.161 | bisanhydrobacterioruberin hydratase | ||
| EC 4.2.1.162 | 6-deoxy-6-sulfo-D-gluconate dehydratase | ||
| EC 4.2.1.163 | 2-oxo-hept-4-ene-1,7-dioate hydratase | ||
| EC 4.2.1.164 | dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase | ||
| EC 4.2.1.165 | chlorophyllide a 31-hydratase | ||
| EC 4.2.1.166 | phosphinomethylmalate isomerase | ||
| EC 4.2.1.167 | (R)-2-hydroxyglutaryl-CoA dehydratase | ||
| EC 4.2.1.168 | GDP-4-dehydro-6-deoxy-α-D-mannose 3-dehydratase | ||
| EC 4.2.1.169 | 3-vinyl bacteriochlorophyllide d 31-hydratase | ||
| EC 4.2.1.170 | 2-(ω-methylthio)alkylmalate dehydratase | ||
| EC 4.2.1.171 | cis-L-3-hydroxyproline dehydratase | ||
| EC 4.2.1.172 | trans-4-hydroxy-L-proline dehydratase | ||
| EC 4.2.1.173 | ent-8α-hydroxylabd-13-en-15-yl diphosphate synthase | ||
| EC 4.2.1.174 | peregrinol diphosphate synthase | ||
| EC 4.2.1.175 | (R)-3-(aryl)lactoyl-CoA dehydratase | ||
| EC 4.2.1.176 | L-lyxonate dehydratase | ||
| EC 4.2.1.177 | (2S)-3-sulfopropanediol dehydratase | ||
| EC 4.2.1.178 | difructose-dianhydride-III synthase | ||
| EC 4.2.1.179 | difructose-anhydride-I synthase | ||
| EC 4.2.1.180 | (E)-benzylidenesuccinyl-CoA hydratase | ||
| EC 4.2.1.181 | 3-carboxymethyl-3-hydroxy-acyl-[acp] dehydratase | ||
| EC 4.2.1.182 | phosphomevalonate dehydratase | ||
| EC 4.2.1.183 | etheroleic acid synthase | ||
| EC 4.2.2 | [+] Acting on polysaccharides | ||
| EC 4.2.3 | [+] Acting on phosphates | ||
| EC 4.2.99 | [+] Other carbon-oxygen lyases | ||
| EC 4.3 | [+] | ||
| EC 4.4 | [+] | ||
| EC 4.5 | [+] | ||
| EC 4.6 | [+] | ||
| EC 4.7 | [+] | ||
| EC 4.8 | [+] | ||
| EC 4.98 | [+] | ||
| EC 4.99 | [+] | ||
| EC 5 | [+] | ||
| EC 6 | [+] | ||
| EC 7 | [+] |