EC |
1.1.1.102 |
Accepted name: |
3-dehydrosphinganine reductase |
Reaction: |
sphinganine + NADP+ = 3-dehydrosphinganine + NADPH + H+ |
Other name(s): |
D-3-dehydrosphinganine reductase; D-3-oxosphinganine reductase; DSR; 3-oxosphinganine reductase; 3-oxosphinganine:NADPH oxidoreductase; D-3-oxosphinganine:B-NADPH oxidoreductase |
Systematic name: |
D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37250-36-5 |
References: |
1. |
Stoffel, W., Le Kim, D. and Sticht, G. Biosynthesis of dihydrosphingosine in vitro. Hoppe-Seyler's Z. Physiol. Chem. 349 (1968) 664–670. [PMID: 4386961] |
2. |
Stoffel, W., Le Kim, D. and Sticht, G. Metabolism of sphingosine bases. 8. Distribution, isolation and properties of D-3-oxosphinganine reductase. Stereospecificity of the NADPH-dependent reaction of 3-oxodihydrospingosine (2-amino-1-hydroxyoctadecane-3-one). Hoppe-Seyler's Z. Physiol. Chem. 349 (1968) 1637–1644. [PMID: 4387676] |
|
[EC 1.1.1.102 created 1972] |
|
|
|
|