EC |
1.1.1.169 |
Accepted name: |
2-dehydropantoate 2-reductase |
Reaction: |
(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+ |
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For diagram of the early stages of CoA biosynthesis, click here |
Glossary: |
pantoate = 2,4-dihydroxy-3,3-dimethylbutanoate |
Other name(s): |
2-oxopantoate reductase; 2-ketopantoate reductase; 2-ketopantoic acid reductase; ketopantoate reductase; ketopantoic acid reductase |
Systematic name: |
(R)-pantoate:NADP+ 2-oxidoreductase |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37211-74-8 |
References: |
1. |
King, H.L., Jr., Dyar, R.E. and Wilken, D.R. Ketopantoyl lactone and ketopantoic acid reductases. Characterization of the reactions and purification of two forms of ketopantoyl lactone reductase. J. Biol. Chem. 247 (1972) 4689–4695. [PMID: 4603075] |
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[EC 1.1.1.169 created 1976] |
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