| EC |
1.1.1.185 |
| Accepted name: |
L-glycol dehydrogenase |
| Reaction: |
an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+ |
| Other name(s): |
glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase; L-(+)-glycol:NAD(P) oxidoreductase; L-glycol:NAD(P) dehydrogenase |
| Systematic name: |
L-glycol:NAD(P)+ oxidoreductase |
| Comments: |
The 2-hydroxycarbonyl compound formed can be further oxidized to a vicinal dicarbonyl compound. In the reverse direction, vicinal diketones, glyceraldehyde, glyoxal, methylglyoxal, 2-oxo-hydroxyketones and 2-ketoacid esters can be reduced. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 77967-75-0 |
| References: |
| 1. |
Bernardo, A., Burgos, J. and Martin, R. Purification and some properties of L-glycol dehydrogenase from hen's muscle. Biochim. Biophys. Acta 659 (1981) 189–198. [DOI] [PMID: 7018582] |
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| [EC 1.1.1.185 created 1984] |
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