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Your query returned 1 entry. Printable version
EC | 1.1.1.203 | ||||||||
Accepted name: | uronate dehydrogenase | ||||||||
Reaction: | (1) β-D-galacturonate + NAD+ = D-galactaro-1,5-lactone + NADH + H+ (2) β-D-glucuronate + NAD+ = D-glucaro-1,5-lactone + NADH + H+ |
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Other name(s): | uronate:NAD-oxidoreductase; uronic acid dehydrogenase | ||||||||
Systematic name: | uronate:NAD+ 1-oxidoreductase | ||||||||
Comments: | Requires Mg2+. The enzyme, characterized from the bacterium Agrobacterium fabrum, participates in oxidative degradation pathways for galacturonate and glucuronate. The enzyme can only accept the β anomeric form of the substrate [4]. The 1,5-lactone product is rather stable at cytosolic pH and does not hydrolyse spontaneously at a substantial rate. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37250-98-9 | ||||||||
References: |
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