| EC |
1.1.1.21 |
| Accepted name: |
aldose reductase |
| Reaction: |
alditol + NAD(P)+ = aldose + NAD(P)H + H+ |
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For diagram of L-arabinose catabolism, click here |
| Other name(s): |
polyol dehydrogenase (NADP+); ALR2; alditol:NADP+ oxidoreductase; alditol:NADP+ 1-oxidoreductase; NADPH-aldopentose reductase; NADPH-aldose reductase; aldehyde reductase (misleading) |
| Systematic name: |
alditol:NAD(P)+ 1-oxidoreductase |
| Comments: |
Has wide specificity. |
| Links to other databases: |
BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9028-31-3 |
| References: |
| 1. |
Attwood, M.A. and Doughty, C.C. Purification and properties of calf liver aldose reductase. Biochim. Biophys. Acta 370 (1974) 358–368. [DOI] [PMID: 4216364] |
| 2. |
Boghosian, R.A. and McGuinness, E.T. Affinity purification and properties of porcine brain aldose reductase. Biochim. Biophys. Acta 567 (1979) 278–286. [DOI] [PMID: 36151] |
| 3. |
Hers, H.G. L’Aldose-réductase. Biochim. Biophys. Acta 37 (1960) 120–126. [DOI] [PMID: 14401390] |
| 4. |
Scher, B.M. and Horecker, B.L. Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis. Arch. Biochem. Biophys. 116 (1966) 117–128. [PMID: 4381350] |
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| [EC 1.1.1.21 created 1961 (EC 1.1.1.139 created 1972, incorporated 1978), modified 2019] |
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