The Enzyme Database

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Accepted name: 6-pyruvoyltetrahydropterin 2′-reductase
Reaction: 6-lactoyl-5,6,7,8-tetrahydropterin + NADP+ = 6-pyruvoyltetrahydropterin + NADPH + H+
For diagram of 6-pyruvyltetrahydropterin metabolism, click here
Other name(s): 6-pyruvoyltetrahydropterin reductase; 6PPH4(2′-oxo) reductase; 6-pyruvoyl tetrahydropterin (2′-oxo)reductase; 6-pyruvoyl-tetrahydropterin 2′-reductase; pyruvoyl-tetrahydropterin reductase
Systematic name: 6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2′-oxidoreductase
Comments: Not identical with EC sepiapterin reductase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 97089-79-7
1.  Milstien, S. and Kaufman, S. Biosynthesis of tetrahydrobiopterin: conversion of dihydroneopterin triphosphate to tetrahydropterin intermediates. Biochem. Biophys. Res. Commun. 128 (1985) 1099–1107. [DOI] [PMID: 4004850]
[EC created 1989]

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