EC |
1.1.1.235 |
Accepted name: |
8-oxocoformycin reductase |
Reaction: |
coformycin + NADP+ = 8-oxocoformycin + NADPH + H+ |
Other name(s): |
8-ketodeoxycoformycin reductase |
Systematic name: |
coformycin:NADP+ 8-oxidoreductase |
Comments: |
Si-specific with respect to NADPH. Also reduces 8-oxodeoxy-coformycin to the nucleoside antibiotic deoxycoformycin. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 114995-16-3 |
References: |
1. |
Hanvey, J.C., Hawkins, E.S., Baker, D.C. and Suhadolnick, R.J. 8-Ketodeoxycoformycin and 8-ketocoformycin as intermediates in the biosynthesis of 2′-deoxycoformycin and coformycin. Biochemistry 27 (1988) 5790–5795. [PMID: 3052586] |
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[EC 1.1.1.235 created 1992] |
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