||The enzyme from the yeast Saccharomyces cerevisiae catalyses the reduction of a keto group in a number of compounds, forming enantiopure products. Among the substrates are methylglyoxal (which is reduced to (S)-lactaldehyde) [1,2], 3-methylbutanal , hexane-2,5-dione  and 3-chloro-1-phenylpropan-1-one . The enzyme differs from EC 18.104.22.168, methylglyoxal reductase (NADH), which is found in mammals, by its cosubstrate requirement, reaction direction, and enantiomeric preference.
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