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Your query returned 1 entry. Printable version
EC | 1.1.1.325 | ||||
Accepted name: | sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) | ||||
Reaction: | (1) L-threo-7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+ (2) L-threo-tetrahydrobiopterin + 2 NADP+ = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 NADPH + 2 H+ |
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Glossary: | sepiapterin = 2-amino-6-lactoyl-7,8-dihydropteridin-4(3H)-one tetrahydrobiopterin = 5,6,7,8-tetrahydrobiopterin = 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one |
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Systematic name: | L-threo-7,8-dihydrobiopterin:NADP+ oxidoreductase | ||||
Comments: | This enzyme, isolated from the bacterium Chlorobium tepidum, catalyses the final step in the de novo synthesis of tetrahydrobiopterin from GTP. cf. EC 1.1.1.153, sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming). | ||||
Links to other databases: | BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9059-48-7 | ||||
References: |
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