EC |
1.1.1.378 |
Accepted name: |
L-rhamnose 1-dehydrogenase [NAD(P)+] |
Reaction: |
L-rhamnose + NAD(P)+ = L-rhamnono-1,4-lactone + NAD(P)H + H+ |
Systematic name: |
L-rhamnose:NAD(P)+ 1-oxidoreductase |
Comments: |
The enzyme, which occurs in the bacteria Azotobacter vinelandii and Sphingomonas sp. SKA58, is part of the non-phosphorylative degradation pathway for L-rhamnose. The enzyme differs in cofactor specificity from EC 1.1.1.173, L-rhamnose 1-dehydrogenase, which is specific for NAD+ and EC 1.1.1.377, L-rhamnose 1-dehydrogenase (NADP+). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Watanabe, S., Saimura, M. and Makino, K. Eukaryotic and bacterial gene clusters related to an alternative pathway of nonphosphorylated L-rhamnose metabolism. J. Biol. Chem. 283 (2008) 20372–20382. [DOI] [PMID: 18505728] |
2. |
Watanabe, S. and Makino, K. Novel modified version of nonphosphorylated sugar metabolism - an alternative L-rhamnose pathway of Sphingomonas sp. FEBS J. 276 (2009) 1554–1567. [DOI] [PMID: 19187228] |
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[EC 1.1.1.378 created 2014] |
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