The Enzyme Database

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Accepted name: L-gulonate 5-dehydrogenase
Reaction: L-gulonate + NAD+ = D-fructuronate + NADH + H+
Glossary: D-fructuronate = D-arabino-hexuronate
Systematic name: L-gulonate:NAD+ 5-oxidoreductase
Comments: The enzyme, characterized from the bacterium Halomonas elongata, participates in a pathway for L-gulonate degradation.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Cooper, R.A. The pathway for L-gulonate catabolism in Escherichia coli K-12 and Salmonella typhimurium LT-2. FEBS Lett. 115 (1980) 63–67. [DOI] [PMID: 6993236]
2.  Wichelecki, D.J., Vendiola, J.A., Jones, A.M., Al-Obaidi, N., Almo, S.C. and Gerlt, J.A. Investigating the physiological roles of low-efficiency D-mannonate and D-gluconate dehydratases in the enolase superfamily: pathways for the catabolism of L-gulonate and L-idonate. Biochemistry 53 (2014) 5692–5699. [DOI] [PMID: 25145794]
[EC created 2014]

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