| EC |
1.1.1.400 |
| Accepted name: |
2-methyl-1,2-propanediol dehydrogenase |
| Reaction: |
2-methylpropane-1,2-diol + NAD+ = 2-hydroxy-2-methylpropanal + NADH + H+ |
| Other name(s): |
mpdB (gene name) |
| Systematic name: |
2-methylpropane-1,2-diol:NAD+ 1-oxidoreductase |
| Comments: |
This bacterial enzyme is involved in the degradation pathways of the alkene 2-methylpropene and the fuel additive tert-butyl methyl ether (MTBE), a widely occurring groundwater contaminant. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Lopes Ferreira, N., Labbe, D., Monot, F., Fayolle-Guichard, F. and Greer, C.W. Genes involved in the methyl tert-butyl ether (MTBE) metabolic pathway of Mycobacterium austroafricanum IFP 2012. Microbiology 152 (2006) 1361–1374. [DOI] [PMID: 16622053] |
| 2. |
Kottegoda, S., Waligora, E. and Hyman, M. Metabolism of 2-methylpropene (isobutylene) by the aerobic bacterium Mycobacterium sp. strain ELW1. Appl. Environ. Microbiol. 81 (2015) 1966–1976. [DOI] [PMID: 25576605] |
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| [EC 1.1.1.400 created 2016] |
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