| EC |
1.1.1.414 |
| Accepted name: |
L-galactonate 5-dehydrogenase |
| Reaction: |
L-galactonate + NAD+ = D-tagaturonate + NADH + H+ |
| Other name(s): |
lgoD (gene name); lgaC (gene name) |
| Systematic name: |
L-galactonate:NAD+ 5-oxidoreductase |
| Comments: |
The enzyme, reported from the human gut bacteria Escherichia coli and Bacteroides vulgatus, participates in an L-galactonate degradation pathway. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Cooper, R.A. The pathway for L-galactonate catabolism in Escherichia coli K-12. FEBS Lett. 103 (1979) 216–220. [PMID: 381020] |
| 2. |
Kuivanen, J. and Richard, P. The yjjN of E. coli codes for an L-galactonate dehydrogenase and can be used for quantification of L-galactonate and L-gulonate. Appl. Biochem. Biotechnol. 173 (2014) 1829–1835. [PMID: 24861318] |
| 3. |
Hobbs, M.E., Williams, H.J., Hillerich, B., Almo, S.C. and Raushel, F.M. L-Galactose metabolism in Bacteroides vulgatus from the human gut microbiota. Biochemistry 53 (2014) 4661–4670. [DOI] [PMID: 24963813] |
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| [EC 1.1.1.414 created 2018] |
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