The Enzyme Database

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Accepted name: cis-4-hydroxycyclohexanecarboxylate dehydrogenase
Reaction: cis-4-hydroxycyclohexane-1-carboxylate + NAD+ = 4-oxocyclohexane-1-carboxylate + NADH + H+
Glossary: cis-4-hydroxycyclohexane-1-carboxylate = cis-4-hydroxycyclohexanecarboxylate
4-oxocyclohexane-1-carboxylate = 4-oxocyclohexanecarboxylate
Other name(s): chcB2 (gene name)
Systematic name: cis-4-hydroxycyclohexane-1-carboxylate:NAD+ 4-oxidoreductase
Comments: The enzyme from Corynebacterium cyclohexanicum is highly specific for the cis-4-hydroxy derivative. cf. EC, trans-4-hydroxycyclohexanecarboxylate dehydrogenase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Yamamoto, T., Hasegawa, Y., Lau, P.CK. and Iwaki, H. Identification and characterization of a chc gene cluster responsible for the aromatization pathway of cyclohexanecarboxylate degradation in Sinomonas cyclohexanicum ATCC 51369. J. Biosci. Bioeng. 132 (2021) 621–629. [DOI] [PMID: 34583900]
[EC created 2024]

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