| EC |
1.1.1.443 |
| Accepted name: |
questin reductase |
| Reaction: |
questin hydroquinone + NADP+ = questin + NADPH + H+ |
| Glossary: |
questin = 1,6-dihydroxy-8-methoxy-3-methylanthracene-9,10-dione |
| Other name(s): |
gedF (gene name) |
| Systematic name: |
questin hydroquinone:NADP+ 10-oxidoreductase |
| Comments: |
The enzyme, characterized from the fungus Aspergillus terreus, catalyses a step in the biosynthesis of (+)-geodin. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Qi, F., Zhang, W., Xue, Y., Geng, C., Huang, X., Sun, J. and Lu, X. Bienzyme-catalytic and dioxygenation-mediated anthraquinone ring opening. J. Am. Chem. Soc. 143 (2021) 16326–16331. [DOI] [PMID: 34586791] |
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| [EC 1.1.1.443 created 1992 as EC 1.14.13.43, part transferred 2025 to EC 1.1.1.443] |
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