The Enzyme Database

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EC 1.1.1.444     
Accepted name: sulfofucose 1-dehydrogenase
Reaction: sulfofucose + NAD+ = 6-deoxy-6-sulfo-D-galactono-1,5-lactone + NADH + H+
Glossary: sulfofucose = 6-deoxy-6-sulfo-D-galactopyranose
Other name(s): sulfofucose dehydrogenase; SfcH
Systematic name: 6-deoxy-6-sulfo-D-galactopyranose:NAD+ 1-oxidoreductase
Comments: This enzyme, characterized from the bacterium Paracoccus wurundjeri strain Merri, participates in a sulfofucose degradation pathway. Activity with NADP+ is 28% of that with NAD+. cf. EC 1.1.1.390, sulfoquinovose 1-dehydrogenase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Stewart, A.WE., Li, J., Lee, M., Lewis, J.M., Herisse, M., Hofferek, V., McConville, M.J., Pidot, S.J., Scott, N.E. and Williams, S.J. Tandem sulfofucolytic-sulfolactate sulfolyase pathway for catabolism of the rare sulfosugar sulfofucose. mBio 16:e0184025 (2025). [DOI] [PMID: 40823846]
[EC 1.1.1.444 created 2025]
 
 


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