EC |
1.1.1.48 |
Accepted name: |
D-galactose 1-dehydrogenase |
Reaction: |
D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+ |
Other name(s): |
D-galactose dehydrogenase; β-galactose dehydrogenase (ambiguous); NAD+-dependent D-galactose dehydrogenase |
Systematic name: |
D-galactose:NAD+ 1-oxidoreductase |
Comments: |
This enzyme is part of the De Ley-Doudoroff pathway, which is used by some bacteria during growth on D-galactose. |
Links to other databases: |
BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9028-54-0 |
References: |
1. |
De Ley, J. and Doudoroff, M. The metabolism of D-galactose in Pseudomonas saccharophila. J. Biol. Chem. 227 (1957) 745–757. [PMID: 13462997] |
2. |
Hu, A.S.L. and Cline, A.L. The regulation of some sugar dehydrogenases in a pseudomonad. Biochim. Biophys. Acta 93 (1964) 237–245. [DOI] [PMID: 14251301] |
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[EC 1.1.1.48 created 1961, modified 2011] |
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