EC |
1.1.1.76 |
Accepted name: |
(S,S)-butanediol dehydrogenase |
Reaction: |
(2S,3S)-butane-2,3-diol + NAD+ = (S)-acetoin + NADH + H+ |
Other name(s): |
L-butanediol dehydrogenase; L-BDH; L(+)-2,3-butanediol dehydrogenase (L-acetoin forming); (S)-acetoin reductase [(S,S)-butane-2,3-diol forming] |
Systematic name: |
(S,S)-butane-2,3-diol:NAD+ oxidoreductase |
Comments: |
This enzyme catalyses the reversible reduction of (S)-acetoin to (S,S)-butane-2,3-diol. It can also catalyse the irreversible reduction of diacetyl to (S)-acetoin. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
References: |
1. |
Taylor, M.B. and Juni, E. Stereoisomeric specificities of 2,3-butanediol dehydrogenase. Biochim. Biophys. Acta 39 (1960) 448–457. [DOI] [PMID: 13837186] |
2. |
Carballo, J., Martin, R., Bernardo, A. and Gonzalez, J. Purification, characterization and some properties of diacetyl(acetoin) reductase from Enterobacter aerogenes. Eur. J. Biochem. 198 (1991) 327–332. [DOI] [PMID: 2040298] |
3. |
Takusagawa, Y., Otagiri, M., Ui, S., Ohtsuki, T., Mimura, A., Ohkuma, M. and Kudo, T. Purification and characterization of L-2,3-butanediol dehydrogenase of Brevibacterium saccharolyticum C-1012 expressed in Escherichia coli. Biosci. Biotechnol. Biochem. 65 (2001) 1876–1878. [DOI] [PMID: 11577733] |
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[EC 1.1.1.76 created 1972, modified 2010] |
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